3cs7

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(New page: '''Unreleased structure''' The entry 3cs7 is ON HOLD Authors: Alexander, R.S. Description: FACTOR XA IN COMPLEX WITH THE INHIBITOR 1-(4-methoxyphenyl)-6-(4-(1-(pyrrolidin-1-ylmethyl)cy...)
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'''Unreleased structure'''
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{{Seed}}
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[[Image:3cs7.jpg|left|200px]]
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The entry 3cs7 is ON HOLD
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{{STRUCTURE_3cs7| PDB=3cs7 | SCENE= }}
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Authors: Alexander, R.S.
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===FACTOR XA IN COMPLEX WITH THE INHIBITOR 1-(4-methoxyphenyl)-6-(4-(1-(pyrrolidin-1-ylmethyl)cyclopropyl)phenyl)-3-(trifluoromethyl)-5,6-dihydro-1H-pyrazolo[3,4-c]pyridin-7(4H)-one===
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Description: FACTOR XA IN COMPLEX WITH THE INHIBITOR 1-(4-methoxyphenyl)-6-(4-(1-(pyrrolidin-1-ylmethyl)cyclopropyl)phenyl)-3-(trifluoromethyl)-5,6-dihydro-1H-pyrazolo[3,4-c]pyridin-7(4H)-one
 
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{{ABSTRACT_PUBMED_18550370}}
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 11 09:33:48 2008''
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==About this Structure==
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3CS7 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CS7 OCA].
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==Reference==
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Achieving structural diversity using the perpendicular conformation of alpha-substituted phenylcyclopropanes to mimic the bioactive conformation of ortho-substituted biphenyl P4 moieties: Discovery of novel, highly potent inhibitors of Factor Xa., Qiao JX, Cheney DL, Alexander RS, Smallwood AM, King SR, He K, Rendina AR, Luettgen JM, Knabb RM, Wexler RR, Lam PY, Bioorg Med Chem Lett. 2008 May 29;. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18550370 18550370]
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[[Category: Coagulation factor Xa]]
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[[Category: Homo sapiens]]
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[[Category: Protein complex]]
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[[Category: Alexander, R S.]]
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[[Category: Blood coagulation]]
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[[Category: Blood coagulation factor]]
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[[Category: Calcium]]
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[[Category: Calcium-binding]]
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[[Category: Cleavage on pair of basic residue]]
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[[Category: Egf-like domain]]
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[[Category: Gamma-carboxyglutamic acid]]
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[[Category: Glycoprotein]]
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[[Category: Hydrolase]]
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[[Category: Hydroxylation]]
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[[Category: Plasma]]
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[[Category: Polymorphism]]
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[[Category: Protease]]
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[[Category: Protein inhibitor complex]]
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[[Category: Serine protease]]
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[[Category: Zymogen]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 9 10:24:58 2008''

Revision as of 07:24, 9 July 2008

Image:3cs7.jpg

Template:STRUCTURE 3cs7

FACTOR XA IN COMPLEX WITH THE INHIBITOR 1-(4-methoxyphenyl)-6-(4-(1-(pyrrolidin-1-ylmethyl)cyclopropyl)phenyl)-3-(trifluoromethyl)-5,6-dihydro-1H-pyrazolo[3,4-c]pyridin-7(4H)-one

Template:ABSTRACT PUBMED 18550370

About this Structure

3CS7 is a Protein complex structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Achieving structural diversity using the perpendicular conformation of alpha-substituted phenylcyclopropanes to mimic the bioactive conformation of ortho-substituted biphenyl P4 moieties: Discovery of novel, highly potent inhibitors of Factor Xa., Qiao JX, Cheney DL, Alexander RS, Smallwood AM, King SR, He K, Rendina AR, Luettgen JM, Knabb RM, Wexler RR, Lam PY, Bioorg Med Chem Lett. 2008 May 29;. PMID:18550370

Page seeded by OCA on Wed Jul 9 10:24:58 2008

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