3nib
From Proteopedia
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| - | {{Seed}} | ||
| - | [[Image:3nib.jpg|left|200px]] | ||
| - | < | + | ==Teg14 Apo== |
| - | + | <StructureSection load='3nib' size='340' side='right'caption='[[3nib]], [[Resolution|resolution]] 2.70Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3nib]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Uncultured_soil_bacterium Uncultured soil bacterium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NIB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3NIB FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7Å</td></tr> | |
| - | -- | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NHE:2-[N-CYCLOHEXYLAMINO]ETHANE+SULFONIC+ACID'>NHE</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3nib FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nib OCA], [https://pdbe.org/3nib PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3nib RCSB], [https://www.ebi.ac.uk/pdbsum/3nib PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3nib ProSAT]</span></td></tr> | |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/B7T1D9_9BACT B7T1D9_9BACT] | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | The TEG gene cluster was recently isolated from an environmental DNA library and is predicted to encode the biosynthesis of a polysulfated glycopeptide congener. Three closely related sulfotransferases found in the TEG gene cluster (Teg12, Teg13 and Teg14) have been shown to sulfate the teicoplanin aglycone at three unique sites. Crystal structures of the first sulfotransferase from the TEG cluster, Teg12, in complex with the teicoplanin aglycone and its desulfated cosubstrate PAP have recently been reported [Bick et al. (2010), Biochemistry, 49, 4159-4168]. Here, the 2.7 A resolution crystal structure of the apo form of Teg14 is reported. Teg14 sulfates the hydroxyphenylglycine at position 4 in the teicoplanin aglycone. The Teg14 structure is discussed and is compared with those of other bacterial 3'-phosphoadenosine 5'-phosphosulfate-dependent sulfotransferases. | ||
| - | + | The 2.7 A resolution structure of the glycopeptide sulfotransferase Teg14.,Bick MJ, Banik JJ, Darst SA, Brady SF Acta Crystallogr D Biol Crystallogr. 2010 Dec;66(Pt 12):1278-86. Epub 2010, Nov 16. PMID:21123867<ref>PMID:21123867</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | == | + | </div> |
| - | + | <div class="pdbe-citations 3nib" style="background-color:#fffaf0;"></div> | |
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Uncultured soil bacterium]] | [[Category: Uncultured soil bacterium]] | ||
| - | [[Category: Banik | + | [[Category: Banik JJ]] |
| - | [[Category: Bick | + | [[Category: Bick MJ]] |
| - | [[Category: Brady | + | [[Category: Brady SF]] |
| - | [[Category: Darst | + | [[Category: Darst SA]] |
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Current revision
Teg14 Apo
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