3nib

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[[Image:3nib.png|left|200px]]
 
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==Teg14 Apo==
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The line below this paragraph, containing "STRUCTURE_3nib", creates the "Structure Box" on the page.
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<StructureSection load='3nib' size='340' side='right'caption='[[3nib]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3nib]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Uncultured_soil_bacterium Uncultured soil bacterium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NIB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3NIB FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NHE:2-[N-CYCLOHEXYLAMINO]ETHANE+SULFONIC+ACID'>NHE</scene></td></tr>
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{{STRUCTURE_3nib| PDB=3nib | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3nib FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nib OCA], [https://pdbe.org/3nib PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3nib RCSB], [https://www.ebi.ac.uk/pdbsum/3nib PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3nib ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/B7T1D9_9BACT B7T1D9_9BACT]
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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The TEG gene cluster was recently isolated from an environmental DNA library and is predicted to encode the biosynthesis of a polysulfated glycopeptide congener. Three closely related sulfotransferases found in the TEG gene cluster (Teg12, Teg13 and Teg14) have been shown to sulfate the teicoplanin aglycone at three unique sites. Crystal structures of the first sulfotransferase from the TEG cluster, Teg12, in complex with the teicoplanin aglycone and its desulfated cosubstrate PAP have recently been reported [Bick et al. (2010), Biochemistry, 49, 4159-4168]. Here, the 2.7 A resolution crystal structure of the apo form of Teg14 is reported. Teg14 sulfates the hydroxyphenylglycine at position 4 in the teicoplanin aglycone. The Teg14 structure is discussed and is compared with those of other bacterial 3'-phosphoadenosine 5'-phosphosulfate-dependent sulfotransferases.
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===Teg14 Apo===
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The 2.7 A resolution structure of the glycopeptide sulfotransferase Teg14.,Bick MJ, Banik JJ, Darst SA, Brady SF Acta Crystallogr D Biol Crystallogr. 2010 Dec;66(Pt 12):1278-86. Epub 2010, Nov 16. PMID:21123867<ref>PMID:21123867</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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The line below this paragraph, {{ABSTRACT_PUBMED_21123867}}, adds the Publication Abstract to the page
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<div class="pdbe-citations 3nib" style="background-color:#fffaf0;"></div>
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(as it appears on PubMed at http://www.pubmed.gov), where 21123867 is the PubMed ID number.
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== References ==
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<references/>
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{{ABSTRACT_PUBMED_21123867}}
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__TOC__
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</StructureSection>
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==About this Structure==
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[[Category: Large Structures]]
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[[3nib]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Uncultured_soil_bacterium Uncultured soil bacterium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NIB OCA].
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==Reference==
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<ref group="xtra">PMID:021123867</ref><references group="xtra"/>
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[[Category: Uncultured soil bacterium]]
[[Category: Uncultured soil bacterium]]
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[[Category: Banik, J J.]]
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[[Category: Banik JJ]]
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[[Category: Bick, M J.]]
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[[Category: Bick MJ]]
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[[Category: Brady, S F.]]
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[[Category: Brady SF]]
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[[Category: Darst, S A.]]
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[[Category: Darst SA]]
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[[Category: Antibiotic transferase]]
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[[Category: Transferase]]
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Current revision

Teg14 Apo

PDB ID 3nib

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