3d9h

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[[Image:3d9h.png|left|200px]]
 
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{{STRUCTURE_3d9h| PDB=3d9h | SCENE= }}
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==Crystal Structure of the Splice Variant of Human ASB9 (hASB9-2), an Ankyrin Repeat Protein==
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<StructureSection load='3d9h' size='340' side='right'caption='[[3d9h]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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===Crystal Structure of the Splice Variant of Human ASB9 (hASB9-2), an Ankyrin Repeat Protein===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3d9h]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D9H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3D9H FirstGlance]. <br>
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{{ABSTRACT_PUBMED_022418839}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3d9h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3d9h OCA], [https://pdbe.org/3d9h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3d9h RCSB], [https://www.ebi.ac.uk/pdbsum/3d9h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3d9h ProSAT]</span></td></tr>
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==About this Structure==
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</table>
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[[3d9h]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D9H OCA].
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== Function ==
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[https://www.uniprot.org/uniprot/ASB9_HUMAN ASB9_HUMAN] Substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes at least two forms of creatine kinase, CKB and CKMT1A.<ref>PMID:20302626</ref> <ref>PMID:22418839</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d9/3d9h_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3d9h ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Fan, S.]]
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[[Category: Large Structures]]
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[[Category: Fei, X.]]
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[[Category: Fan S]]
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[[Category: Gu, X.]]
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[[Category: Fei X]]
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[[Category: Ji, C.]]
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[[Category: Gu X]]
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[[Category: Zhang, C.]]
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[[Category: Ji C]]
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[[Category: Alpha-helice]]
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[[Category: Zhang C]]
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[[Category: Ank repeat]]
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[[Category: Asb9]]
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[[Category: L-shaped]]
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[[Category: Protein binding]]
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[[Category: Structural protein]]
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Current revision

Crystal Structure of the Splice Variant of Human ASB9 (hASB9-2), an Ankyrin Repeat Protein

PDB ID 3d9h

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