3d1c

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "3d1c" [edit=sysop:move=sysop])
Current revision (08:56, 30 October 2024) (edit) (undo)
 
(7 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:3d1c.png|left|200px]]
 
-
{{STRUCTURE_3d1c| PDB=3d1c | SCENE= }}
+
==Crystal structure of Flavin-containing Putative Monooxygenase (NP_373108.1) from STAPHYLOCOCCUS AUREUS MU50 at 2.40 A resolution==
 +
<StructureSection load='3d1c' size='340' side='right'caption='[[3d1c]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[3d1c]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_Mu50 Staphylococcus aureus subsp. aureus Mu50]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D1C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3D1C FirstGlance]. <br>
 +
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
 +
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3d1c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3d1c OCA], [https://pdbe.org/3d1c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3d1c RCSB], [https://www.ebi.ac.uk/pdbsum/3d1c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3d1c ProSAT], [https://www.topsan.org/Proteins/JCSG/3d1c TOPSAN]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/A0A0H3JN45_STAAN A0A0H3JN45_STAAN]
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d1/3d1c_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3d1c ConSurf].
 +
<div style="clear:both"></div>
 +
<div style="background-color:#fffaf0;">
 +
== Publication Abstract from PubMed ==
 +
Flavin-containing Monooxygenase (FMO) catalyzed the oxygenation of broad spectrum of substrates. FMO can also serve as biocatalysts in the Baeyer-Villiger reaction in organic synthesis. Here we report the high-resolution crystal structure of a Baeyer-Villiger Flavin-containing Monooxygenase (BVFMO) from methicillin- and vancomycin-resistant Staphylococcus aureus strain MU50. The structure of Staphylococcus aureus FMO should facilitate further development of BVFMO as biocatalysts. A possible role of Staphylococcus aureus FMO in methicillin and vancomycin resistance is discussed. (c) Proteins 2014;. (c) 2014 Wiley Periodicals, Inc.
-
===Crystal structure of Flavin-containing Putative Monooxygenase (NP_373108.1) from STAPHYLOCOCCUS AUREUS MU50 at 2.40 A resolution===
+
Crystal structure of a Baeyer-Villiger Flavin-containing monooxygenase from Staphylococcus aureus MRSA strain MU50.,Hwang WC, Xu Q, Wu B, Godzik A Proteins. 2014 Aug 5. doi: 10.1002/prot.24661. PMID:25092800<ref>PMID:25092800</ref>
-
 
+
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
-
==About this Structure==
+
</div>
-
[[3d1c]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D1C OCA].
+
<div class="pdbe-citations 3d1c" style="background-color:#fffaf0;"></div>
-
[[Category: Staphylococcus aureus]]
+
== References ==
-
[[Category: JCSG, Joint Center for Structural Genomics.]]
+
<references/>
-
[[Category: Flavin-containing putative monooxygenase]]
+
__TOC__
-
[[Category: Jcsg]]
+
</StructureSection>
-
[[Category: Joint center for structural genomic]]
+
[[Category: Large Structures]]
-
[[Category: Np_373108 1]]
+
[[Category: Staphylococcus aureus subsp. aureus Mu50]]
-
[[Category: Oxidoreductase]]
+
-
[[Category: Protein structure initiative]]
+
-
[[Category: Psi-2]]
+
-
[[Category: Pyridine nucleotide-disulphide oxidoreductase]]
+
-
[[Category: Structural genomic]]
+

Current revision

Crystal structure of Flavin-containing Putative Monooxygenase (NP_373108.1) from STAPHYLOCOCCUS AUREUS MU50 at 2.40 A resolution

PDB ID 3d1c

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://proteopedia.org/wiki/index.php/3d1c"
Personal tools