1v4n
From Proteopedia
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| - | [[Image:1v4n.gif|left|200px]] | ||
| - | + | ==Structure of 5'-deoxy-5'-methylthioadenosine phosphorylase homologue from Sulfolobus tokodaii== | |
| - | + | <StructureSection load='1v4n' size='340' side='right'caption='[[1v4n]], [[Resolution|resolution]] 2.45Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[1v4n]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Sulfurisphaera_tokodaii Sulfurisphaera tokodaii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V4N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1V4N FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.45Å</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1v4n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v4n OCA], [https://pdbe.org/1v4n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1v4n RCSB], [https://www.ebi.ac.uk/pdbsum/1v4n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1v4n ProSAT]</span></td></tr> | |
| - | + | </table> | |
| - | + | == Function == | |
| - | + | [https://www.uniprot.org/uniprot/F9VN03_SULTO F9VN03_SULTO] Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.[HAMAP-Rule:MF_01963] | |
| - | + | == Evolutionary Conservation == | |
| - | + | [[Image:Consurf_key_small.gif|200px|right]] | |
| - | + | Check<jmol> | |
| - | + | <jmolCheckbox> | |
| - | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v4/1v4n_consurf.spt"</scriptWhenChecked> | |
| - | == | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> |
| - | + | <text>to colour the structure by Evolutionary Conservation</text> | |
| - | + | </jmolCheckbox> | |
| - | [[Category: | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1v4n ConSurf]. |
| - | [[Category: | + | <div style="clear:both"></div> |
| - | [[Category: Kawarabayasi | + | __TOC__ |
| - | [[Category: Kitago | + | </StructureSection> |
| - | [[Category: Sakai | + | [[Category: Large Structures]] |
| - | [[Category: Tanaka | + | [[Category: Sulfurisphaera tokodaii]] |
| - | [[Category: Tsujimura | + | [[Category: Kawarabayasi Y]] |
| - | [[Category: Watanabe | + | [[Category: Kitago Y]] |
| - | [[Category: Yao | + | [[Category: Sakai N]] |
| - | [[Category: Yasutake | + | [[Category: Tanaka I]] |
| - | + | [[Category: Tsujimura M]] | |
| - | + | [[Category: Watanabe N]] | |
| - | + | [[Category: Yao M]] | |
| - | + | [[Category: Yasutake Y]] | |
Current revision
Structure of 5'-deoxy-5'-methylthioadenosine phosphorylase homologue from Sulfolobus tokodaii
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