9c5c
From Proteopedia
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(New page: '''Unreleased structure''' The entry 9c5c is ON HOLD Authors: Description: Category: Unreleased Structures) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of Human Adaptor Protein Complex AP-3 in the Apo State== | |
| - | + | <StructureSection load='9c5c' size='340' side='right'caption='[[9c5c]], [[Resolution|resolution]] 3.60Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[9c5c]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9C5C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9C5C FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.6Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9c5c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9c5c OCA], [https://pdbe.org/9c5c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9c5c RCSB], [https://www.ebi.ac.uk/pdbsum/9c5c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9c5c ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/AP3D1_HUMAN AP3D1_HUMAN] Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Baker RW]] | ||
| + | [[Category: Begley MC]] | ||
Current revision
Structure of Human Adaptor Protein Complex AP-3 in the Apo State
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