2b4l

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{{Seed}}
 
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[[Image:2b4l.png|left|200px]]
 
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==Crystal structure of the binding protein OpuAC in complex with glycine betaine==
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The line below this paragraph, containing "STRUCTURE_2b4l", creates the "Structure Box" on the page.
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<StructureSection load='2b4l' size='340' side='right'caption='[[2b4l]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2b4l]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B4L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2B4L FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BET:TRIMETHYL+GLYCINE'>BET</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
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{{STRUCTURE_2b4l| PDB=2b4l | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2b4l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b4l OCA], [https://pdbe.org/2b4l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2b4l RCSB], [https://www.ebi.ac.uk/pdbsum/2b4l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2b4l ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/OPUAC_BACSU OPUAC_BACSU] Involved in a multicomponent binding-protein-dependent transport system for glycine betaine.<ref>PMID:7622480</ref> <ref>PMID:8752321</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b4/2b4l_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2b4l ConSurf].
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<div style="clear:both"></div>
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===Crystal structure of the binding protein OpuAC in complex with glycine betaine===
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==See Also==
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*[[ABC transporter 3D structures|ABC transporter 3D structures]]
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== References ==
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<references/>
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 16445940 is the PubMed ID number.
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</StructureSection>
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{{ABSTRACT_PUBMED_16445940}}
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==About this Structure==
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2B4L is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B4L OCA].
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==Reference==
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Molecular determinants for substrate specificity of the ligand-binding protein OpuAC from Bacillus subtilis for the compatible solutes glycine betaine and proline betaine., Horn C, Sohn-Bosser L, Breed J, Welte W, Schmitt L, Bremer E, J Mol Biol. 2006 Mar 24;357(2):592-606. Epub 2006 Jan 13. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16445940 16445940]
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[[Category: Bacillus subtilis]]
[[Category: Bacillus subtilis]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Breed, J.]]
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[[Category: Breed J]]
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[[Category: Bremer, E.]]
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[[Category: Bremer E]]
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[[Category: Horn, C.]]
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[[Category: Horn C]]
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[[Category: Schmitt, L.]]
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[[Category: Schmitt L]]
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[[Category: Sohn-Boesser, L.]]
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[[Category: Sohn-Boesser L]]
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[[Category: Welte, W.]]
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[[Category: Welte W]]
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[[Category: Abc-transporter]]
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[[Category: Closed liganded]]
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[[Category: Compatible solute]]
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[[Category: Substrate-binding protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 13:47:36 2008''
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Current revision

Crystal structure of the binding protein OpuAC in complex with glycine betaine

PDB ID 2b4l

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