2dms

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
(New page: 200px<br /><applet load="2dms" size="450" color="white" frame="true" align="right" spinBox="true" caption="2dms" /> '''Solution structure of the homeobox domain of...)
Current revision (18:44, 29 May 2024) (edit) (undo)
 
(13 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2dms.gif|left|200px]]<br /><applet load="2dms" size="450" color="white" frame="true" align="right" spinBox="true"
 
-
caption="2dms" />
 
-
'''Solution structure of the homeobox domain of Homeobox protein OTX2'''<br />
 
-
==About this Structure==
+
==Solution structure of the homeobox domain of Homeobox protein OTX2==
-
2DMS is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2DMS OCA].
+
<StructureSection load='2dms' size='340' side='right'caption='[[2dms]]' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[2dms]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DMS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DMS FirstGlance]. <br>
 +
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dms FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dms OCA], [https://pdbe.org/2dms PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dms RCSB], [https://www.ebi.ac.uk/pdbsum/2dms PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dms ProSAT], [https://www.topsan.org/Proteins/RSGI/2dms TOPSAN]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/OTX2_MOUSE OTX2_MOUSE] Probably plays a role in the development of the brain and the sense organs. Can bind to the BCD target sequence (BTS): 5'-TCTAATCCC-3'.
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dm/2dms_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2dms ConSurf].
 +
<div style="clear:both"></div>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
-
[[Category: Single protein]]
+
[[Category: Inoue M]]
-
[[Category: Inoue, M.]]
+
[[Category: Kigawa T]]
-
[[Category: Kigawa, T.]]
+
[[Category: Koshiba S]]
-
[[Category: Koshiba, S.]]
+
[[Category: Ohnishi S]]
-
[[Category: Ohnishi, S.]]
+
[[Category: Saito K]]
-
[[Category: RSGI, RIKEN.Structural.Genomics/Proteomics.Initiative.]]
+
[[Category: Yokoyama S]]
-
[[Category: Saito, K.]]
+
-
[[Category: Yokoyama, S.]]
+
-
[[Category: homeobox domain]]
+
-
[[Category: national project on protein structural and functional analyses]]
+
-
[[Category: nppsfa]]
+
-
[[Category: riken structural genomics/proteomics initiative]]
+
-
[[Category: rsgi]]
+
-
[[Category: structural genomics]]
+
-
[[Category: three helices with the dna binding helix-turn-helix motif ]]
+
-
 
+
-
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Wed Nov 21 09:40:32 2007''
+

Current revision

Solution structure of the homeobox domain of Homeobox protein OTX2

PDB ID 2dms

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://proteopedia.org/wiki/index.php/2dms"
Personal tools