3elm

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Revision as of 06:53, 26 July 2012

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Template:STRUCTURE 3elm

Contents 1 Crystal Structure of MMP-13 Complexed with Inhibitor 24f 2 About this Structure 3 See Also 4 Reference

Crystal Structure of MMP-13 Complexed with Inhibitor 24f

Template:ABSTRACT PUBMED 19422229

About this Structure

3elm is a 2 chain structure of Matrix metalloproteinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Matrix metalloproteinase

Reference

• Monovich LG, Tommasi RA, Fujimoto RA, Blancuzzi V, Clark K, Cornell WD, Doti R, Doughty J, Fang J, Farley D, Fitt J, Ganu V, Goldberg R, Goldstein R, Lavoie S, Kulathila R, Macchia W, Parker DT, Melton R, O'Byrne E, Pastor G, Pellas T, Quadros E, Reel N, Roland DM, Sakane Y, Singh H, Skiles J, Somers J, Toscano K, Wigg A, Zhou S, Zhu L, Shieh WC, Xue S, McQuire LW. Discovery of potent, selective, and orally active carboxylic acid based inhibitors of matrix metalloproteinase-13. J Med Chem. 2009 Jun 11;52(11):3523-38. PMID:19422229 doi:10.1021/jm801394m