MHC I 3D structures
From Proteopedia
(Difference between revisions)
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**[[4pj9]] - hMHC I (mutant) + β-2-microglobulin + TCR<br /> | **[[4pj9]] - hMHC I (mutant) + β-2-microglobulin + TCR<br /> | ||
**[[8esb]] - hMHC I /β-2-microglobulin/peptide – Cryo EM<br /> | **[[8esb]] - hMHC I /β-2-microglobulin/peptide – Cryo EM<br /> | ||
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*Non-human MHC I ternary complex | *Non-human MHC I ternary complex | ||
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**[[3jts]], [[6hwj]] - rmMHC I + β-2-microglobulin + peptide – Rhesus macaque<br /> | **[[3jts]], [[6hwj]] - rmMHC I + β-2-microglobulin + peptide – Rhesus macaque<br /> | ||
**[[6lah]], [[6lam]], [[6lb2]], [[6lt6]] - rmMHC I (mutant) + β-2-microglobulin + lysophospholipid <br /> | **[[6lah]], [[6lam]], [[6lb2]], [[6lt6]] - rmMHC I (mutant) + β-2-microglobulin + lysophospholipid <br /> | ||
| - | **[[3qq3]], [[3qq4]], [[5h94]], [[5nq1]], [[6a6h]], [[6kwk]], [[6kwl]], [[6kwo]], [[6lf8]], [[6lf9]], [[7em9]], [[7ema]], [[7emb]], [[7emc]], [[7emd]], [[8gqv]], [[8gqw]] - pMHC I + β-2-microglobulin + peptide – pig<br /> | + | **[[3qq3]], [[3qq4]], [[5h94]], [[5nq1]], [[6a6h]], [[6kwk]], [[6kwl]], [[6kwo]], [[6lf8]], [[6lf9]], [[7em9]], [[7ema]], [[7emb]], [[7emc]], [[7emd]], [[8gqv]], [[8gqw]], [[9ul1]] - pMHC I + β-2-microglobulin + peptide – pig<br /> |
**[[6kwn]] - pMHC I (mutant) + β-2-microglobulin + peptide<br /> | **[[6kwn]] - pMHC I (mutant) + β-2-microglobulin + peptide<br /> | ||
**[[1kjv]], [[1kjm]], [[1ed3]] – MHC I + β-2-microglobulin + peptide - rat<br /> | **[[1kjv]], [[1kjm]], [[1ed3]] – MHC I + β-2-microglobulin + peptide - rat<br /> | ||
**[[2oi9]] - mMHC I + T cell receptor + peptide <br /> | **[[2oi9]] - mMHC I + T cell receptor + peptide <br /> | ||
| - | **[[1bz9]], [[1ffn]], [[1ffo]], [[1ffp]], [[1fg2]], [[1g7p]], [[1g7q]], [[1hoc]], [[1juf]], [[1jpf]], [[1jpg]], [[1k8d]], [[1kbg]], [[1kpu]], [[1kpv]], [[1inq]], [[1ld9]], [[1lek]], [[1leg]], [[1lk2]], [[1n3n]], [[1n59]], [[1n5a]], [[1nan]], [[1qlf]], [[1rjy]], [[1rjz]], [[1rk0]], [[1rk1]], [[1s7q]], [[1s7r]], [[1s7s]], [[1s7t]], [[1s7u]], [[1s7v]], [[1s7w]], [[1s7x]], [[1t0m]], [[1t0n]], [[1vac]], [[1vad]], [[1vgk]], [[1wbx]], [[1wby]], [[1wbz]], [[1yn6]], [[1yn7]], [[1zhb]], [[1zt1]], [[1zt7]], [[2cii]], [[2e7l]], [[2f74]], [[2ffo]], [[2mha]], [[2ve6]], [[2zok]], [[2zol]], [[2zsv]], [[2zsw]], [[3buy]], [[3cc5]], [[3cch]], [[3ch1]], [[3cpl]], [[3e6f]], [[3ecb]], [[3ftg]], [[3fol]], [[3l3h]], [[3quk]], [[3qul]], [[3rol]], [[3roo]], [[3tbs]], [[3tbt]], [[3tbv]], [[3tbw]], [[3tid]], [[3tie]], [[3tby]], [[4nsk]], [[4pg9]], [[4pgd]], [[4pge]], [[5j6h]], [[5opi]], [[5ts1]], [[6g9r]], [[6gb5]], [[6gb6]], [[6gb7]], [[6jq2]], [[6jq3]], [[6npr]], [[6x00]], [[7lfi]], [[7n5q]], [[8d5j]] - mMHC I + β-2-microglobulin + peptide<br /> | + | **[[1bz9]], [[1ffn]], [[1ffo]], [[1ffp]], [[1fg2]], [[1g7p]], [[1g7q]], [[1hoc]], [[1juf]], [[1jpf]], [[1jpg]], [[1k8d]], [[1kbg]], [[1kpu]], [[1kpv]], [[1inq]], [[1ld9]], [[1lek]], [[1leg]], [[1lk2]], [[1n3n]], [[1n59]], [[1n5a]], [[1nan]], [[1qlf]], [[1rjy]], [[1rjz]], [[1rk0]], [[1rk1]], [[1s7q]], [[1s7r]], [[1s7s]], [[1s7t]], [[1s7u]], [[1s7v]], [[1s7w]], [[1s7x]], [[1t0m]], [[1t0n]], [[1vac]], [[1vad]], [[1vgk]], [[1wbx]], [[1wby]], [[1wbz]], [[1yn6]], [[1yn7]], [[1zhb]], [[1zt1]], [[1zt7]], [[2cii]], [[2e7l]], [[2f74]], [[2ffo]], [[2mha]], [[2ve6]], [[2zok]], [[2zol]], [[2zsv]], [[2zsw]], [[3buy]], [[3cc5]], [[3cch]], [[3ch1]], [[3cpl]], [[3e6f]], [[3ecb]], [[3ftg]], [[3fol]], [[3l3h]], [[3quk]], [[3qul]], [[3rol]], [[3roo]], [[3tbs]], [[3tbt]], [[3tbv]], [[3tbw]], [[3tid]], [[3tie]], [[3tby]], [[4nsk]], [[4pg9]], [[4pgd]], [[4pge]], [[5j6h]], [[5opi]], [[5ts1]], [[6g9r]], [[6gb5]], [[6gb6]], [[6gb7]], [[6jq2]], [[6jq3]], [[6npr]], [[6x00]], [[7ji2]], [[7lfi]], [[7n5q]], [[8d5j]] - mMHC I + β-2-microglobulin + peptide<br /> |
**[[2qri]] - mMHC I/β-2-microglobulin/peptide<br /> | **[[2qri]] - mMHC I/β-2-microglobulin/peptide<br /> | ||
**[[2qrs]], [[2qrt]] - mMHC I (mutant)/β-2-microglobulin/peptide<br /> | **[[2qrs]], [[2qrt]] - mMHC I (mutant)/β-2-microglobulin/peptide<br /> | ||
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**[[7cpo]] – MHC I + β-2-microglobulin + peptide – Anolis carolinensis<br /> | **[[7cpo]] – MHC I + β-2-microglobulin + peptide – Anolis carolinensis<br /> | ||
**[[6ilc]], [[6ile]], [[6ilf]], [[6ilg]] – MHC I + β-2-microglobulin + peptide – flying fox<br /> | **[[6ilc]], [[6ile]], [[6ilf]], [[6ilg]] – MHC I + β-2-microglobulin + peptide – flying fox<br /> | ||
| - | **[[2yez]], [[3bev]], [[3bew]], [[3rwc]], [[3rwd]], [[3rwe]], [[3rwf]], [[3rwg]], [[3rwh]], [[3rwi]], [[3rwj]], [[4cvx]], [[4cvz]], [[4d0b]], [[4d0c]], [[4d0d]], [[4cw1]], [[4zfz]], [[5ad0]], [[6iwg]], [[6irl]], [[6kx9]], [[6lhf]], [[6lhg]], [[6lhh]], [[7wbg]], [[7wbi]] – cMHC I + β-2-microglobulin + peptide<br /> | + | **[[2yez]], [[3bev]], [[3bew]], [[3rwc]], [[3rwd]], [[3rwe]], [[3rwf]], [[3rwg]], [[3rwh]], [[3rwi]], [[3rwj]], [[4cvx]], [[4cvz]], [[4d0b]], [[4d0c]], [[4d0d]], [[4cw1]], [[4zfz]], [[5ad0]], [[6iwg]], [[6irl]], [[6kx9]], [[6lhf]], [[6lhg]], [[6lhh]], [[7wbg]], [[7wbi]], [[8z0h]] – cMHC I + β-2-microglobulin + peptide<br /> |
**[[4e0r]], [[4g42]] – cMHC I (mutant) + β-2-microglobulin + peptide<br /> | **[[4e0r]], [[4g42]] – cMHC I (mutant) + β-2-microglobulin + peptide<br /> | ||
**[[7zqj]], [[7zqi]] – MHC I + β-2-microglobulin + peptide – warbler<br /> | **[[7zqj]], [[7zqi]] – MHC I + β-2-microglobulin + peptide – warbler<br /> | ||
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*MHC I quaternary complex | *MHC I quaternary complex | ||
| - | **[[1lp9 | + | **[[1lp9]], [[1oga]], [[1qrn]], [[2bnq]], [[2bnr]], [[2esv]], [[2f53]], [[2f54]], [[2gj6]], [[2j8u]], [[2p5e]], [[2p5w]], [[2pye]], [[3d39]], [[3d3v]], [[3ffc]], [[3gsn]], [[3h9s]], [[3mv7]], [[3mv9]], [[3o4l]], [[3qdg]], [[3qdj]], [[3qdm]], [[3qeq]], [[4eup]], [[4ftv]], [[4jfd]], [[4jry]], [[4pri]], [[4qrp]], [[5brz]], [[5c08]], [[5e9d]], [[5wkh]], [[6amu]], [[6avf]], [[6avg]], [[6bj8]], [[6d78]], [[6dkp]], [[6eqa]], [[6eqb]], [[6g9q]], [[6pue]], [[6puf]], [[6pug]], [[6pui]], [[6puj]], [[6puk]], [[6pul]], [[6pum]], [[6pvc]], [[6pvd]], [[6px6]], [[6q3s]], [[6r2l]], [[6rsy]], [[6tmo]], [[6tro]], [[6uk2]], [[6uk4]], [[6uln]], [[6ulr]], [[6uon]], [[6uz1]], [[6vm7]], [[6vm8]], [[6vm9]], [[6vqo]], [[6vma]], [[6vmc]], [[6vmx]], [[6vrm]], [[6vrn]], [[6zky]], [[7lfk]], [[7lfl]], [[7lfm]], [[7ndt]], [[7nme]], [[7nmf]], [[7nmg]], [[7ow5]], [[7ow6]], [[7pb2]], [[7q99]], [[7q9a]], [[7q9b]], [[7qpj]], [[7rk7]], [[7rrg]], [[7su9]], [[8cx4]], [[8i5c]], [[8qfy]], [[8rlu]], [[8rlv]], [[8rro]], [[8rym]], [[8ryn]], [[8ryo]], [[8ryp]], [[8ryq]], [[8shi]], [[8wte]], [[8wul]], [[9d95]], [[9gv6]], [[9hi7]] - hMHC I + T cell receptor + beta-2-microglobulin + peptide<br /> |
**[[2jcc]], [[2uwe]], [[3kxf]], [[3mv8]] - hMHC I (mutant) + T cell receptor + β-2-microglobulin + peptide<br /> | **[[2jcc]], [[2uwe]], [[3kxf]], [[3mv8]] - hMHC I (mutant) + T cell receptor + β-2-microglobulin + peptide<br /> | ||
| - | **[[7pbe]], [[8gom]], [[8gon]] - hMHC I + T cell receptor + β-2-microglobulin + SARS peptide<br /> | + | **[[7n1e]], [[7n1f]], [[7n6e]], [[7pbe]], [[7rtr]], [[8dnt]], [[8gom]], [[8gon]], [[8rj5]], [[8rji]], [[9j4u]] - hMHC I + T cell receptor + β-2-microglobulin + SARS peptide<br /> |
| + | **[[2vlj]], [[2vlk]], [[2vll]], [[2vlr]], [[6mt3]], [[6mt4]], [[6mt5]], [[6mt6]], [[6mtm]], [[7n4k]], [[7n5c]], [[7n5p]], [[7n5q]], [[8en8]], [[8enh]] - hMHC I + T cell receptor + β-2-microglobulin + influenza A peptide<br /> | ||
| + | **[[3vxm]], [[3vxs]], [[4mji]], [[5nmf]], [[6bj2]], [[6bj3]], [[7dzm]], [[7dzn]], [[7r80]], [[8f5a]], [[8gvb]], [[8gvg]], [[8gvi]], [[9k2r]] - hMHC I + T cell receptor + β-2-microglobulin + HIV peptide<br /> | ||
| + | **[[9o06]], [[9o07]] - hMHC I + T cell receptor + β-2-microglobulin + flavin derivative<br /> | ||
| + | **[[9bys]] - hMHC I + T cell receptor + β-2-microglobulin + ribitol derivative<br /> | ||
**[[7phr]], [[8es8]], [[8es9]] - hMHC I + T cell receptor + β-2-microglobulin + peptide + CD3 – Cryo EM<br / > | **[[7phr]], [[8es8]], [[8es9]] - hMHC I + T cell receptor + β-2-microglobulin + peptide + CD3 – Cryo EM<br / > | ||
**[[1im9]], [[1p7q]], [[6ewc]] - hMHC I + leukocyte immunoglobulin-like receptor + β-2-microglobulin + peptide<br /> | **[[1im9]], [[1p7q]], [[6ewc]] - hMHC I + leukocyte immunoglobulin-like receptor + β-2-microglobulin + peptide<br /> | ||
| - | **[[5t6z]], [[6v3j]], [[7k80]], [[7k81]] - hMHC I + KIR3DL1 + β-2-microglobulin + peptide<br /> | + | **[[5t6z]], [[6v3j]], [[7k80]], [[7k81]], [[9bl2]], [[9bl3]], [[9bl4]], [[9bl5]], [[9bl6]], [[9bl9]], [[9bla]], [[9d96]] - hMHC I + KIR3DL1 + β-2-microglobulin + influenza A peptide<br /> |
| - | **[[6pa1]] - hMHC I + KIR2DL2 + β-2-microglobulin + peptide<br /> | + | **[[6pa1]] - hMHC I + KIR2DL2 + β-2-microglobulin + influenza A peptide<br /> |
| - | **[[6pag]] - hMHC I + KIR2DL3 + β-2-microglobulin + peptide<br /> | + | **[[6pag]] - hMHC I + KIR2DL3 + β-2-microglobulin + influenza A peptide<br /> |
**[[6aee]], [[6k60]] - hMHC I + LIR-1 + β-2-microglobulin + peptide<br /> | **[[6aee]], [[6k60]] - hMHC I + LIR-1 + β-2-microglobulin + peptide<br /> | ||
**[[6ewo]] - hMHC I + LIR-1 + synemin + β-2-microglobulin + peptide<br /> | **[[6ewo]] - hMHC I + LIR-1 + synemin + β-2-microglobulin + peptide<br /> | ||
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**[[1im3]] - hMHC I + β-2-microglobulin + cytomegalovirus protein US2 + peptide<br /> | **[[1im3]] - hMHC I + β-2-microglobulin + cytomegalovirus protein US2 + peptide<br /> | ||
**[[3cdg]], [[3cii]] - hMHC I + β-2-microglobulin + CD94 ectodomain + NKG2A/NKG2B integral membrane protein + peptide<br /> | **[[3cdg]], [[3cii]] - hMHC I + β-2-microglobulin + CD94 ectodomain + NKG2A/NKG2B integral membrane protein + peptide<br /> | ||
| - | **[[1w72]], [[3cvh]], [[3gjf]], [[3hae]], [[5d2n]], [[6id4]], [[6uj9]], [[6w51]], [[7bbg]], [[7bh8]], [[7re7]], [[8eb2]] - hMHC I + β-2-microglobulin + antibody + peptide<br /> | + | **[[1w72]], [[3cvh]], [[3gjf]], [[3hae]], [[5d2n]], [[6id4]], [[6uj9]], [[6w51]], [[7bbg]], [[7bh8]], [[7re7]], [[8eb2]], [[8fja]], [[8fjb]], [[8t7r]], [[8tnj]], [[9pix]], [[9pkf]] - hMHC I + β-2-microglobulin + antibody + peptide<br /> |
**[[7t0l]] - hMHC I (mutant) + β-2-microglobulin + antibody + peptide<br /> | **[[7t0l]] - hMHC I (mutant) + β-2-microglobulin + antibody + peptide<br /> | ||
| + | **[[9pkv]] - hMHC I + β-2-microglobulin + antibody + Vhh + peptide – Cryo EM<br /> | ||
**[[7sr3]], [[7sr5]], [[7srk]] - hMHC I /β-2-microglobulin/peptide + Vhh<br /> | **[[7sr3]], [[7sr5]], [[7srk]] - hMHC I /β-2-microglobulin/peptide + Vhh<br /> | ||
| + | **[[8ek5]] - hMHC I + β-2-microglobulin + peptide + scFv<br /> | ||
**[[7duu]] - hMHC I + β-2-microglobulin + KIR receptor + peptide<br /> | **[[7duu]] - hMHC I + β-2-microglobulin + KIR receptor + peptide<br /> | ||
**[[4e5x]] - hMHC I + β-2-microglobulin + E3-19K + peptide<br /> | **[[4e5x]] - hMHC I + β-2-microglobulin + E3-19K + peptide<br /> | ||
| + | **[[9rcv]] - hMHC I in peptide-loading complex – Cryo EM<br /> | ||
**[[7byd]] - rmMHC I + β-2-microglobulin + TCR + peptide<br /> | **[[7byd]] - rmMHC I + β-2-microglobulin + TCR + peptide<br /> | ||
**[[1fo0]], [[1g6r]], [[1mwa]], [[1nam]], [[2ckb]], [[2z31]], [[3pqy]], [[7jwi]] - mMHC I + T cell receptor + β-2-microglobulin + peptide<br /> | **[[1fo0]], [[1g6r]], [[1mwa]], [[1nam]], [[2ckb]], [[2z31]], [[3pqy]], [[7jwi]] - mMHC I + T cell receptor + β-2-microglobulin + peptide<br /> | ||
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**[[5oqf]], [[5oqg]], [[5oqh]], [[5oqi]], [[6apn]], [[6e1i]], [[7sqp]], [[7sr3]], [[7sr4]], [[7sr5]], [[7srk]], [[7sro]], [[7ssh]], [[7st3]], [[7stg]], [[9c6v]], [[9c6w]], [[9c6x]] – hMHC I/hB-2-microglobulin/peptide<br /> | **[[5oqf]], [[5oqg]], [[5oqh]], [[5oqi]], [[6apn]], [[6e1i]], [[7sqp]], [[7sr3]], [[7sr4]], [[7sr5]], [[7srk]], [[7sro]], [[7ssh]], [[7st3]], [[7stg]], [[9c6v]], [[9c6w]], [[9c6x]] – hMHC I/hB-2-microglobulin/peptide<br /> | ||
| + | **[[8esb]] – hMHC I/hB-2-microglobulin/peptide – Cryo EM<br /> | ||
**[[2qri]], [[2qrs]], [[2qrt]], [[3nwm]] – mMHC I (mutant)/B-2-microglobulin/peptide<br /> | **[[2qri]], [[2qrs]], [[2qrt]], [[3nwm]] – mMHC I (mutant)/B-2-microglobulin/peptide<br /> | ||
Current revision
3D structures of MHC I
Updated on 09-December-2025
