1odf
From Proteopedia
(New page: 200px<br /> <applet load="1odf" size="450" color="white" frame="true" align="right" spinBox="true" caption="1odf, resolution 2.25Å" /> '''STRUCTURE OF YGR205...) |
|||
| Line 8: | Line 8: | ||
==About this Structure== | ==About this Structure== | ||
| - | 1ODF is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]] with SO4 and GOL as [[http://en.wikipedia.org/wiki/ligands ligands]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1ODF OCA]]. | + | 1ODF is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]] with SO4 and GOL as [[http://en.wikipedia.org/wiki/ligands ligands]]. Structure known Active Site: AC1. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1ODF OCA]]. |
==Reference== | ==Reference== | ||
| Line 21: | Line 21: | ||
[[Category: yeast protein]] | [[Category: yeast protein]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 13:36:02 2007'' |
Revision as of 11:31, 30 October 2007
|
STRUCTURE OF YGR205W PROTEIN.
Overview
The protein product of the YGR205w gene of Saccharomyces cerevisiae was, targeted as part of our yeast structural genomics project. YGR205w codes, for a small (290 amino acids) protein with unknown structure and function., The only recognizable sequence feature is the presence of a Walker A motif, (P loop) indicating a possible nucleotide binding/converting function. We, determined the three-dimensional crystal structure of Se-methionine, substituted protein using multiple anomalous diffraction. The structure, revealed a well known mononucleotide fold and strong resemblance to the, structure of small metabolite phosphorylating enzymes such as pantothenate, and phosphoribulo kinase. Biochemical experiments show that YGR205w binds, specifically ATP and, less tightly, ADP. The structure also ... [(full description)]
About this Structure
1ODF is a [Single protein] structure of sequence from [Saccharomyces cerevisiae] with SO4 and GOL as [ligands]. Structure known Active Site: AC1. Full crystallographic information is available from [OCA].
Reference
Crystal structure of the YGR205w protein from Saccharomyces cerevisiae: close structural resemblance to E. coli pantothenate kinase., de La Sierra-Gallay IL, Collinet B, Graille M, Quevillon-Cheruel S, Liger D, Minard P, Blondeau K, Henckes G, Aufrere R, Leulliot N, Zhou CZ, Sorel I, Ferrer JL, Poupon A, Janin J, van Tilbeurgh H, Proteins. 2004 Mar 1;54(4):776-83. PMID:14997573
Page seeded by OCA on Tue Oct 30 13:36:02 2007
