3q4c
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | + | [[Image:3q4c.jpg|left|200px]] | |
| - | The | + | <!-- |
| + | The line below this paragraph, containing "STRUCTURE_3q4c", creates the "Structure Box" on the page. | ||
| + | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| + | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| + | or leave the SCENE parameter empty for the default display. | ||
| + | --> | ||
| + | {{STRUCTURE_3q4c| PDB=3q4c | SCENE= }} | ||
| - | + | ===Crystal Structure of Wild Type BRAF kinase domain in complex with organometallic inhibitor CNS292=== | |
| - | + | ||
| + | <!-- | ||
| + | The line below this paragraph, {{ABSTRACT_PUBMED_19371126}}, adds the Publication Abstract to the page | ||
| + | (as it appears on PubMed at http://www.pubmed.gov), where 19371126 is the PubMed ID number. | ||
| + | --> | ||
| + | {{ABSTRACT_PUBMED_19371126}} | ||
| + | |||
| + | ==About this Structure== | ||
| + | [[3q4c]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q4C OCA]. | ||
| + | |||
| + | ==Reference== | ||
| + | <ref group="xtra">PMID:19371126</ref><references group="xtra"/> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Non-specific serine/threonine protein kinase]] | ||
| + | [[Category: Marmorstein, R.]] | ||
| + | [[Category: Meggers, E.]] | ||
| + | [[Category: Pagano, N.]] | ||
| + | [[Category: Pregman, H.]] | ||
| + | [[Category: Qin, J.]] | ||
| + | [[Category: Streu, C.]] | ||
| + | [[Category: Xie, P.]] | ||
Revision as of 06:58, 2 March 2011
Crystal Structure of Wild Type BRAF kinase domain in complex with organometallic inhibitor CNS292
Template:ABSTRACT PUBMED 19371126
About this Structure
3q4c is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Xie P, Streu C, Qin J, Bregman H, Pagano N, Meggers E, Marmorstein R. The crystal structure of BRAF in complex with an organoruthenium inhibitor reveals a mechanism for inhibition of an active form of BRAF kinase. Biochemistry. 2009 Jun 16;48(23):5187-98. PMID:19371126 doi:10.1021/bi802067u
