2itk
From Proteopedia
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===human Pin1 bound to D-PEPTIDE=== | ===human Pin1 bound to D-PEPTIDE=== | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[2itk]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ITK OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:017518432</ref><ref group="xtra">PMID:021980916</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Peptidylprolyl isomerase]] | [[Category: Peptidylprolyl isomerase]] | ||
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[[Category: Zhang, Y.]] | [[Category: Zhang, Y.]] | ||
[[Category: Isomerase]] | [[Category: Isomerase]] | ||
| + | [[Category: Isomerase-isomerase inhibitor complex]] | ||
[[Category: Pin1]] | [[Category: Pin1]] | ||
[[Category: Ww domain]] | [[Category: Ww domain]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 22 10:25:40 2009'' | ||
Revision as of 12:02, 7 January 2013
human Pin1 bound to D-PEPTIDE
Template:ABSTRACT PUBMED 17518432
About this Structure
2itk is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Zhang Y, Daum S, Wildemann D, Zhou XZ, Verdecia MA, Bowman ME, Lucke C, Hunter T, Lu KP, Fischer G, Noel JP. Structural basis for high-affinity peptide inhibition of human Pin1. ACS Chem Biol. 2007 May 22;2(5):320-8. PMID:17518432 doi:http://dx.doi.org/10.1021/cb7000044
- Xu GG, Zhang Y, Mercedes-Camacho AY, Etzkorn FA. A reduced-amide inhibitor of Pin1 binds in a conformation resembling a twisted-amide transition state. Biochemistry. 2011 Nov 8;50(44):9545-50. Epub 2011 Oct 18. PMID:21980916 doi:10.1021/bi201055c
