2v4x

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "2v4x" [edit=sysop:move=sysop])
Line 1: Line 1:
-
[[Image:2v4x.png|left|200px]]
+
==CRYSTAL STRUCTURE OF JAAGSIEKTE SHEEP RETROVIRUS CAPSID N-TERMINAL DOMAIN==
 +
<StructureSection load='2v4x' size='340' side='right' caption='[[2v4x]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[2v4x]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Jaagsiekte_sheep_retrovirus Jaagsiekte sheep retrovirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V4X OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2V4X FirstGlance]. <br>
 +
</td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
 +
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2v4x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v4x OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2v4x RCSB], [http://www.ebi.ac.uk/pdbsum/2v4x PDBsum]</span></td></tr>
 +
<table>
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v4/2v4x_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
 +
<div style="clear:both"></div>
 +
<div style="background-color:#fffaf0;">
 +
== Publication Abstract from PubMed ==
 +
Jaagsiekte sheep retrovirus is a betaretrovirus and the causative agent of pulmonary adenocarcinoma, a transmissible lung tumour of sheep. Here we report the crystal structure of the capsid amino-terminal domain and examine the self-association properties of Jaagsiekte sheep retrovirus capsid. We find that the structure is remarkably similar to the amino-terminal domain of the alpharetrovirus, avian leukosis virus, revealing a previously undetected evolutionary similarity. Examination of capsid self-association suggests a mode of assembly not driven by the strong capsid carboxy-terminal domain interactions that characterise capsid assembly in the lentiviruses. Based on these data, we propose this structure provides a model for the capsid of betaretroviruses including the HML-2 family of endogenous human betaretroviruses.
-
{{STRUCTURE_2v4x| PDB=2v4x | SCENE= }}
+
Structure of the Capsid Amino-Terminal Domain from the Betaretrovirus, Jaagsiekte Sheep Retrovirus.,Mortuza GB, Goldstone DC, Pashley C, Haire LF, Palmarini M, Taylor WR, Stoye JP, Taylor IA J Mol Biol. 2008 Nov 5. PMID:19007792<ref>PMID:19007792</ref>
-
===CRYSTAL STRUCTURE OF JAAGSIEKTE SHEEP RETROVIRUS CAPSID N-TERMINAL DOMAIN===
+
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
-
 
+
</div>
-
{{ABSTRACT_PUBMED_19007792}}
+
-
 
+
-
==About this Structure==
+
-
[[2v4x]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Jaagsiekte_sheep_retrovirus Jaagsiekte sheep retrovirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V4X OCA].
+
==See Also==
==See Also==
*[[Virus coat protein|Virus coat protein]]
*[[Virus coat protein|Virus coat protein]]
-
 
+
== References ==
-
==Reference==
+
<references/>
-
<ref group="xtra">PMID:019007792</ref><references group="xtra"/>
+
__TOC__
 +
</StructureSection>
[[Category: Jaagsiekte sheep retrovirus]]
[[Category: Jaagsiekte sheep retrovirus]]
[[Category: Goldstone, D C.]]
[[Category: Goldstone, D C.]]

Revision as of 09:12, 29 September 2014

CRYSTAL STRUCTURE OF JAAGSIEKTE SHEEP RETROVIRUS CAPSID N-TERMINAL DOMAIN

2v4x, resolution 1.50Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://proteopedia.org/wiki/index.php/2v4x"
Views
Personal tools
Navigation
Toolbox