4x5t
From Proteopedia
(Difference between revisions)
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| - | ''' | + | ==alpha 1 glycine receptor transmembrane structure fused to the extracellular domain of GLIC== |
| - | + | <StructureSection load='4x5t' size='340' side='right' caption='[[4x5t]], [[Resolution|resolution]] 3.50Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4x5t]] is a 5 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X5T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4X5T FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4x5t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4x5t OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4x5t RCSB], [http://www.ebi.ac.uk/pdbsum/4x5t PDBsum]</span></td></tr> | |
| - | + | </table> | |
| - | [[Category: | + | == Function == |
| - | [[Category: Delarue M]] | + | [[http://www.uniprot.org/uniprot/GLIC_GLOVI GLIC_GLOVI]] Cationic channel with similar permeabilities for Na(+) and K(+), that is activated by an increase of the proton concentration on the extracellular side. Displays no permeability for chloride ions. Shows slow kinetics of activation, no desensitization and a single channel conductance of 8 pS. Might contribute to adaptation to external pH change.<ref>PMID:17167423</ref> |
| - | [[Category: Sauguet L]] | + | == References == |
| - | [[Category: | + | <references/> |
| - | [[Category: | + | __TOC__ |
| + | </StructureSection> | ||
| + | [[Category: Corringer, P J]] | ||
| + | [[Category: Delarue, M]] | ||
| + | [[Category: Huon, C]] | ||
| + | [[Category: Sauguet, L]] | ||
| + | [[Category: Cys-loop]] | ||
| + | [[Category: Glycine receptor]] | ||
| + | [[Category: Receptor pentameric]] | ||
| + | [[Category: Signaling protein]] | ||
| + | [[Category: Transmembrane receptor]] | ||
Revision as of 14:06, 25 February 2015
alpha 1 glycine receptor transmembrane structure fused to the extracellular domain of GLIC
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