2pyp

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 4: Line 4:
|PDB= 2pyp |SIZE=350|CAPTION= <scene name='initialview01'>2pyp</scene>, resolution 1.9&Aring;
|PDB= 2pyp |SIZE=350|CAPTION= <scene name='initialview01'>2pyp</scene>, resolution 1.9&Aring;
|SITE=
|SITE=
-
|LIGAND= <scene name='pdbligand=HC4:4'-HYDROXYCINNAMIC ACID'>HC4</scene>
+
|LIGAND= <scene name='pdbligand=HC4:4&#39;-HYDROXYCINNAMIC ACID'>HC4</scene>
|ACTIVITY=
|ACTIVITY=
|GENE=
|GENE=
Line 39: Line 39:
[[Category: photoreceptor]]
[[Category: photoreceptor]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:19:37 2008''
+
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 23 15:41:44 2008''

Revision as of 13:41, 23 March 2008

Image:2pyp.jpg


PDB ID 2pyp

Drag the structure with the mouse to rotate
, resolution 1.9Å
Ligands:
Coordinates: save as pdb, mmCIF, xml



PHOTOACTIVE YELLOW PROTEIN, PHOTOSTATIONARY STATE, 50% GROUND STATE, 50% BLEACHED


Overview

The blue-light photoreceptor photoactive yellow protein (PYP) undergoes a self-contained light cycle. The atomic structure of the bleached signaling intermediate in the light cycle of PYP was determined by millisecond time-resolved, multiwavelength Laue crystallography and simultaneous optical spectroscopy. Light-induced trans-to-cis isomerization of the 4-hydroxycinnamyl chromophore and coupled protein rearrangements produce a new set of active-site hydrogen bonds. An arginine gateway opens, allowing solvent exposure and protonation of the chromophore's phenolic oxygen. Resulting changes in shape, hydrogen bonding, and electrostatic potential at the protein surface form a likely basis for signal transduction. The structural results suggest a general framework for the interpretation of protein photocycles.

About this Structure

2PYP is a Single protein structure of sequence from Halorhodospira halophila. Full crystallographic information is available from OCA.

Reference

Structure of a protein photocycle intermediate by millisecond time-resolved crystallography., Genick UK, Borgstahl GE, Ng K, Ren Z, Pradervand C, Burke PM, Srajer V, Teng TY, Schildkamp W, McRee DE, Moffat K, Getzoff ED, Science. 1997 Mar 7;275(5305):1471-5. PMID:9045611

Page seeded by OCA on Sun Mar 23 15:41:44 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://proteopedia.org/wiki/index.php/2pyp"
Personal tools