3f8s

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'''Unreleased structure'''
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{{Seed}}
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[[Image:3f8s.jpg|left|200px]]
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The entry 3f8s is ON HOLD until Nov 13 2010
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{{STRUCTURE_3f8s| PDB=3f8s | SCENE= }}
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Authors: Ammirati, M.J., Liu, S., Piotrowski, D.W.
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===Crystal structure of dipeptidyl peptidase IV in complex with inhibitor===
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Description: Crystal structure of dipeptidyl peptidase IV in complex with inhibitor
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 24 11:29:16 2008''
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{{ABSTRACT_PUBMED_19275964}}
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==About this Structure==
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3F8S is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F8S OCA].
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==Reference==
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<ref group="xtra">PMID:19275964</ref><references group="xtra"/>
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[[Category: Dipeptidyl-peptidase IV]]
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[[Category: Homo sapiens]]
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[[Category: Ammirati, M J.]]
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[[Category: Liu, S.]]
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[[Category: Piotrowski, D W.]]
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[[Category: Aminopeptidase]]
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[[Category: Complex]]
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[[Category: Dipeptidyl peptidase 4]]
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[[Category: Glycoprotein]]
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[[Category: Hydrolase]]
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[[Category: Membrane]]
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[[Category: Protease]]
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[[Category: Secreted]]
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[[Category: Serine protease]]
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[[Category: Signal-anchor]]
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[[Category: Transmembrane]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jun 25 09:15:51 2009''

Revision as of 06:15, 25 June 2009

Image:3f8s.jpg

Template:STRUCTURE 3f8s

Crystal structure of dipeptidyl peptidase IV in complex with inhibitor

Template:ABSTRACT PUBMED 19275964

About this Structure

3F8S is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Ammirati MJ, Andrews KM, Boyer DD, Brodeur AM, Danley DE, Doran SD, Hulin B, Liu S, McPherson RK, Orena SJ, Parker JC, Polivkova J, Qiu X, Soglia CB, Treadway JL, VanVolkenburg MA, Wilder DC, Piotrowski DW. (3,3-Difluoro-pyrrolidin-1-yl)-[(2S,4S)-(4-(4-pyrimidin-2-yl-piperazin-1-y l)-pyrrolidin-2-yl]-methanone: a potent, selective, orally active dipeptidyl peptidase IV inhibitor. Bioorg Med Chem Lett. 2009 Apr 1;19(7):1991-5. Epub 2009 Feb 13. PMID:19275964 doi:10.1016/j.bmcl.2009.02.041

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