3cse

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Template:STRUCTURE 3cse

Candida glabrata Dihydrofolate Reductase complexed with NADPH and 2,4-diamino-5-(3-(2,5-dimethoxyphenyl)prop-1-ynyl)-6-ethylpyrimidine (UCP120B)

Template:ABSTRACT PUBMED 18804036

About this Structure

3CSE is a 2 chains structure of sequences from Candida glabrata. Full crystallographic information is available from OCA.

Reference

Structure-guided development of efficacious antifungal agents targeting Candida glabrata dihydrofolate reductase., Liu J, Bolstad DB, Smith AE, Priestley ND, Wright DL, Anderson AC, Chem Biol. 2008 Sep 22;15(9):990-6. PMID:18804036

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