2rdk

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Template:STRUCTURE 2rdk

Five site mutated Cyanovirin-N with Mannose dimer bound

Template:ABSTRACT PUBMED 18436959

About this Structure

2RDK is a Single protein structure of sequence from Nostoc ellipsosporum. Full crystallographic information is available from OCA.

Reference

Conformational gating of dimannose binding to the antiviral protein cyanovirin revealed from the crystal structure at 1.35 A resolution., Fromme R, Katiliene Z, Fromme P, Ghirlanda G, Protein Sci. 2008 May;17(5):939-44. PMID:18436959

A monovalent mutant of cyanovirin-N provides insight into the role of multiple interactions with gp120 for antiviral activity., Fromme R, Katiliene Z, Giomarelli B, Bogani F, Mc Mahon J, Mori T, Fromme P, Ghirlanda G, Biochemistry. 2007 Aug 14;46(32):9199-207. Epub 2007 Jul 18. PMID:17636873

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