2rdk

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Image:2rdk.png

Template:STRUCTURE 2rdk

Five site mutated Cyanovirin-N with Mannose dimer bound

Template:ABSTRACT PUBMED 18436959

About this Structure

2RDK is a 2 chains structure of sequences from Nostoc ellipsosporum. Full crystallographic information is available from OCA.

Reference

  • Fromme R, Katiliene Z, Fromme P, Ghirlanda G. Conformational gating of dimannose binding to the antiviral protein cyanovirin revealed from the crystal structure at 1.35 A resolution. Protein Sci. 2008 May;17(5):939-44. PMID:18436959 doi:17/5/939
  • Fromme R, Katiliene Z, Giomarelli B, Bogani F, Mc Mahon J, Mori T, Fromme P, Ghirlanda G. A monovalent mutant of cyanovirin-N provides insight into the role of multiple interactions with gp120 for antiviral activity. Biochemistry. 2007 Aug 14;46(32):9199-207. Epub 2007 Jul 18. PMID:17636873 doi:10.1021/bi700666m

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