3f8s

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Image:3f8s.jpg

Template:STRUCTURE 3f8s

Crystal structure of dipeptidyl peptidase IV in complex with inhibitor

Template:ABSTRACT PUBMED 19275964

About this Structure

3F8S is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Ammirati MJ, Andrews KM, Boyer DD, Brodeur AM, Danley DE, Doran SD, Hulin B, Liu S, McPherson RK, Orena SJ, Parker JC, Polivkova J, Qiu X, Soglia CB, Treadway JL, VanVolkenburg MA, Wilder DC, Piotrowski DW. (3,3-Difluoro-pyrrolidin-1-yl)-[(2S,4S)-(4-(4-pyrimidin-2-yl-piperazin-1-y l)-pyrrolidin-2-yl]-methanone: a potent, selective, orally active dipeptidyl peptidase IV inhibitor. Bioorg Med Chem Lett. 2009 Apr 1;19(7):1991-5. Epub 2009 Feb 13. PMID:19275964 doi:10.1016/j.bmcl.2009.02.041

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