Lipase

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Structure of Pancreatic Lipase (PDB entry 1akn)

3D Structures of Lipase

Updated on 04-July-2017

References

  1. [1] 1HPL PDB SUM
  2. [2] A cross-linked complex between horse pancreatic lipase and colipase
  3. [3] History of Lipids
  4. [4] 1HPL PDB
  5. http://www.pdb.org/pdb/explore/explore.do?structureId=1HPL
  6. http://www.pdb.org/pdb/explore/remediatedSequence.do?structureId=1HPL
  7. http://www.springerlink.com/content/g5h1613440115701/fulltext.pdf
  8. Fundamentals of Biochemistry...
  9. Thomas, A. etc. "Role of the Lid Hydrophobicity Pattern in Pancreatic Lipase Activity", The Journal of Biological Chemistry, 2005 September 22; 270 (48): 40074-40083.
  10. "Colipase". Wikipedia: The Free Encyclopedia. 5 July 2011 [5]
  11. "Colipase Residues..."
  12. Fundamentals of Biochemistry...
  13. Crandall,W., Lowe, M. "Colipase Residues Glu64 and Arg65 Are Essential for Normal Lipase-mediated Fat Digestion in the Presence of Bile Salt Micelles" Journal of Biological Chemistry, 2001, (276) 12505-12512
  14. van Tilbeurgh H, etc."Structure of the pancreatic lipase-procolipase complex", 1992 Sep 10;359(6391):159-62. PMID:1522902.[6]
  15. http://www.pdb.org/pdb/explore/explore.do?structureId=1ETH
  16. http://www.nature.com/nature/journal/v362/n6423/abs/362814a0.html
  17. Sussman JL, Harel M, Frolow F, Oefner C, Goldman A, Toker L, Silman I. Atomic structure of acetylcholinesterase from Torpedo californica: a prototypic acetylcholine-binding protein. Science. 1991 Aug 23;253(5022):872-9. PMID:1678899
  18. Ollis DL, Cheah E, Cygler M, Dijkstra B, Frolow F, Franken SM, Harel M, Remington SJ, Silman I, Schrag J, et al.. The alpha/beta hydrolase fold. Protein Eng. 1992 Apr;5(3):197-211. PMID:1409539
  19. Bourne Y, Martinez C, Kerfelec B, Lombardo D, Chapus C, Cambillau C. Horse pancreatic lipase. The crystal structure refined at 2.3 A resolution. J Mol Biol. 1994 May 20;238(5):709-32. PMID:8182745 doi:http://dx.doi.org/10.1006/jmbi.1994.1331
  20. [7] 1LPB PDB SUM
  21. "Pancreatic lipase". Wikipedia: The Free Encyclopedia. 7 Nov 2011 [8]
  22. Kordik, C., Reitz, A. "Pharmacological Treatment of Obesity: Therapeutic Strategies" Journal of Medicinal Chemistry, 1999 (42).

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