Cytochrome P450 3D structures

3D Structures of Cytochrome P450

Updated on 15-December-2022

{"openlevels":0}

• human P450 1 family

• • 2hi4 – hP4501A2+naphthoflavone - human
    
  • 4i8v - hP4501A1 +naphthoflavone
    
  • 6dwn - hP4501A1 + erlotinib
    
  • 6dwm - hP4501A1 + bergamottin
    
  • 3pm0, 6oyu - hP4501B1+naphthoflavone
    
  • 6iq5, 6o5y - hP4501B1 + inhibitor
    
  • 6oyv - P4501B1 + estradiol - synthetic
    
• human P450 2 family

• • 2pg5, 2pg6, 2pg7 – hP4502A6 (mutant)
    
  • 1pq2 - hP4502C8
    
  • 1og2, 1og5 – hP4502C9 (mutant)
    
  • 7rl2 – hP4502C9 (mutant)) + drug
    
  • 4gqs - hP4502C19 catalytic domain
    
  • 2f9q, 3qm4 – hP4502D6
    
• human P450 2 family complex
  • 3ebs – hP4502A6 (mutant)+phenacetin
    
  • 2fdu, 2fdv, 2fdw, 2fdy - hP4502A6+pyridine derivative
    
  • 1z10 - hP4502A6 catalytic domain+coumarin
    
  • 4ejj - hP4502A6 + nicotine
    
  • 3t3q, 3t3r - hP4502A6 (mutant) + pilocarpine
    
  • 2z10 – hP4502A6+coumarin
    
  • 1z11 - hP4502A6+methoxalen
    
  • 4rui – hP450 2A6 + volatile hydrocarbon
    
  • 3t3s - hP4502A13 + pilocarpine
    
  • 4ejg - hP4502A13 + nicotine
    
  • 4ejh, 4eji - hP4502A13 + pyridine derivative
    
  • 2p85 – hP4502A13 (mutant)+indole
    
  • 3ibd – hP4502B6 (mutant)+4-(4-chlorophenyl)imidazole
    
  • 3ua5 – hP4502B6 (mutant) + amlodipine
    
  • 4i91, 4zv8 - hP4502B6 (mutant) + pinine
    
  • 5wbg - hP4502B6 (mutant) + HIV drug
    
  • 3qoa, 2qu8, 3qu8 – hP450 2B6 (mutant) + inhibitor
    
  • 4rql, 4rrt – hP450 2B6 (mutant) + volatile hydrocarbon
    
  • 5ufg, 5uec, 5uap – hP450 2B6 (mutant) + Br derivative
    
  • 5uda – hP450 2B6 (mutant) + monoterpene borane
    
  • 5e58 – dwP450 2B35 + inhibitor – desert woodrat
    
  • 5e0e – dwP450 2B37 + inhibitor
    
  • 2nnh – hP4502C8+retinoic acid
    
  • 2nni - hP4502C8+montelukast
    
  • 2nnj - hP4502C8+felodipine
    
  • 1r9o – hP4502C9 (mutant)+flurbiprofen
    
  • 5xxi, 5x23, 5x24 - hP4502C9 (mutant) + blood pressure drug
    
  • 5a5i, 5a5j, 5w0c, 5k7k - hP4502C9 + inhibitor
    
  • 4nz2 - hP4502C9 (mutant) + inhibitor
    
  • 3tbg, 4wnw – hP4502D6 + thioridazine
    
  • 6csb - hP4502D6 (mutant) + thioridazine
    
  • 3tda – hP4502D6 + prinomastat
    
  • 6csd - hP4502D6 (mutant) + prinomastat
    
  • 4wnt - hP4502D6 + ajmalicine
    
  • 4wnu, 4wnv - hP4502D6 + quinine derivative
    
  • 5tft, 5tfu, 4xry, 4xrz - hP4502D6 + Bace1 inhibitor
    
  • 3gph, 3koh, 3lc4 – hP4502E1 fragment +imidazole derivative
    
  • 3e6i – hP4502E1 fragment+indazole
    
  • 3e4e – hP4502E1 fragment+methylpyrazole
    
  • 3t3z - hP4502E1 + pilocarpine
    
  • 3czh, 3dl9, 3c6g – hP4502R1+vitamin D
    
• human P450 3 family
  • 1tqn, 1w0e, 1w0f, 1w0g – hP4503A4
    
  • 5vcc, 5vcd, 4l3q - hP4503A4 (mutant)
    
  • 2v0m – hP4503A4+ anti-fungal drug
    
  • 2j0d - hP4503A4+ antibiotic
    
  • 3nxu, 3tjs - hP4503A4+ anti-HIV drug
    
  • 4i4g, 4i4h, 4k9t, 4k9u, 4k9v, 4k9w, 4k9x, 5vc0, 5vce - hP4503A4 (mutant) + anti-HIV drug
    
  • 5g5j - hP4503A4 + anti-diabetic drug
    
  • 6oo9, 6ooa, 6oob - hP4503A4 + anti-hypertension drug
    
  • 3ua1 - hP4503A4 + ergocryptine
    
  • 5vcg - hP4503A4 (mutant) + ergocryptine
    
  • 4ny4, 4d7d, 4d78, 4d75, 4d6z, 6bdm, 6bdk, 6bdi, 6bdh, 6bd8, 6bd7, 6bd6, 6bd5, 6bcz, 6ma8, 6ma7, 6ma6, 6dal, 6daj, 6dag, 6dac, 6dab, 6daa, 6da8, 6da5, 6da3, 6da2, 6une, 6ung, 6unh, 6uni, 6unj, 6unk, 6unl, 6unm, 7ks8, 7ksa, 7ksh, 7kvh, 7kvi, 7kvj, 7kvn, 7kvo, 7kvs, 7uay, 7uaz, 7uf9, 7ufb, 7ufc, 7ufd, 7ufe, 7uff - hP4503A4 + inhibitor
    
  • 5te8 - hP4503A4 + sedation drug
    
  • 5a1p, 5a1r - hP4503A4 + progesterone
    
  • 7lxl - hP4503A4 + testosterone
    
  • 6mjm - hP4503A5
    
  • 5veu, 7sv2 - hP4503A5 + inhibitor
    
  • 7lad - hP4503A7 + drug
    
  • 7mk8 - hP4503A7 + dithiothreitol
    
• human P450 7 family
  • 3dax – hP4507A1
    
  • 3sn5 - hP4507A1 + cholest-4-en-3-one
• human P450 11 family
  • 6m7x, 7e7f - hP450 CYP11B1 + drug
    
  • 4dvq - hP450 CYP11B2 + corticosterone
    
  • 4fdh, 7m8v - hP450 CYP11B2 + drug
    
  • 4zgx, 6xz8, 6xz9 - hP450 CYP11B2 + inhibitor
    
• human P450 17 A1 family (steroid 17-α-hydroxylase 17,20 lyase)
  • 5uys, 3ruk, 6chi, 6cir, 6ciz, 6wr0, 6ww0 - hP450 C17 + abiraterone derivative
    
  • 4nkv, 6wr1 - hP450 C17 (mutant) + abiraterone derivative
    
  • 5irq - hP450 C17 + orteronel
    
  • 5irv - hP450 C17 + inhibitor
    
  • 4nkw, 4nkz - hP450 C17 (mutant) + pregnenolone derivative
    
  • 4nkx, 4nky - hP450 C17 (mutant) + progesterone derivative
    
  • 3swz - hP450 C17 + drug
    
• human P450 19 family (aromatase)
  • 5jkv - hP45019A1
    
  • 5jkw - hP45019A1 + testosterone
    
  • 3eqm, 3s79, 4kq8, 5jl6, 5jl7, 5jl9 - hP45019A1+androstenedione
    
  • 3s7s - hP45019A1 + exemestane
    
  • 4gl5, 4gl7 - hP45019A1 + inhibitor
• human P450 46 family
  • 2q9f – hP45046A1+cholesterol
    
  • 2q9d, 2q9g - hP45046A1
    
  • 2vn0 – hP450105A1+troglitazone
    
  • 2zby - hP450105A1 (mutant)
• P450 from Mycobacterium tuberculosis or sterol 14-α demethylase; CYP121 is mycocyclosin synthase
  • 2vku, 1h5z – MtP450 CYP51 - Mycobacterium tuberculosis
    
  • 2ci0, 2cib, 1u13 - MtP450 CYP51 (mutant)
    
  • 1x8v - MtP450 CYP51 (mutant)+estriol
    
  • 1ea1 - MtP450 CYP51 (mutant)+ fluconazole
    
  • 1e9x - MtP450 CYP51 (mutant)+ phenylimidazole
    
  • 3g5f, 3g5h, 2ij5, 1n40 – MtP450 CYP121
    
  • 3cxv, 3cxx, 3cxy, 3cxz, 3cy0, 3cy1 - MtP450 CYP121 (mutant)
    
  • 2ij7 - MtP450 CYP121+fluconazole
    
  • 1n4g, 4ktf, 4ktj, 4ktk, 4ktl, 6geo, 6geq - MtP450 CYP121+pyrazole derivative
    
  • 4ict, 4ips, 4ipw, 4iq7, 4iq9, 5wp2 - MtP450 CYP121 + piperazine derivative
    
  • 6upg, 6upi - MtP450 CYP121 + cyf-4-ome
    
  • 6rq0, 6rq1, 6rq3, 6rq5, 6rq6, 6rq8, 6rq9, 6rqb, 6rqd, 6rqe - MtP450 CYP121 + dicyclo-Tyr derivative
    
  • 4g1x, 4g2g, 4g44, 4g45, 4g46, 4g47, 4g48, 5ibg, 5ibh, 5ibi, 5ibj, 5ibd, 5ibe, 5ibf, 5edt, 5o4k, 5o4l, 5op9, 5opa, 6geo, 6geq, 6te7, 6tet, 6tev, 7nqm, 7nqn, 7nqo - MtP450 CYP121 + inhibitor
    
  • 3ivi, 3iw0, 3ivy – MtP450 CYP125
    
  • 3iw1 - MtP450 CYP125+androstenedione
    
  • 3iw2 - MtP450 CYP125+econazole
    
  • 2uvn - MtP450 CYP130+econazole
    
  • 2wgy – MtP450 CYP130 (mutant)
    
  • 2w09, 2w0b, 2w0a - MtP450 CYP130 (mutant)+pyridine inhibitor
    
  • 2uuq – MtP450 CYP130
    
  • 5hdi - MtP450 CYP144A1
    
• P450cam or camphor-5 momooxygenase
  • 1dz4, 1dz8, 1dz6, 1dz9, 5cp4, 1phc, 2cpp, 1yrc, 1yrd, 3l61, 3l62, 3l63, 3wrh, 3wri, 3wrk, 6wpl - PpP450cam - Pseudomona putida
    
  • 2qbl, 2qbm, 2qbn, 2gqx, 2gr6, 2frz, 2h7s, 6cp4, 2cp4, 3cp4, 4cp4, 1c8j, 1geb, 2a1o, 3p6q, 3p6r, 3p6s, 3p6t, 3p6u, 3p6v, 3p6w, 3p6x, 4ek1, 5wk7, 6we6, 6wfl – PpP450cam (mutant)
    
  • 2qbo - PpP450cam (mutant)+cyanide
    
  • 1qmq - PpP450cam (mutant)+Ru substrate
    
  • 2h7q - PpP450cam+imidazole
    
  • 1cp4 - PpP450cam+benzene
    
  • 1akd, 1iwi, 1noo, 7cpp, 8cpp, 2zwt, 2zwu, 5ik1 - PpP450cam+1S-camphor derivative
    
  • 1iwj, 1iwk, 2zuh, 2zui, 2zuj, 3fwf, 3fwg, 3fwi, 3fwj - PpP450cam (mutant)+1Scamphor
    
  • 4l49, 4l4a, 4l4b, 4l4c - PpP450cam (mutant)+ camphor
    
  • 4l4d, 4l4e, 4l4f, 4l4g, 5wk9 - PpP450cam (mutant)+ camphor + CN
    
  • 4kky - PpP450cam (mutant)+ camphor + pyrene derivative
    
  • 2l8m – PpP450cam+camphor+CO
    
  • 4g3r – PpP450cam+camphor+NO
    
  • 2fe6, 2fer, 2feu - PpP450cam+Mn protoporphyrin IX
    
  • 1uyu - PpP450cam+ Xe
    
  • 1o76 - PpP450cam+cyanide
    
  • 4cpp - PpP450cam+adamantine
    
  • 5cpp - PpP450cam+adamantanone
    
  • 6cpp - PpP450cam+camphene
    
  • 1p2y, 1p7r - PpP450cam+nicotine
    
  • 1re9, 1rf9 - PpP450cam +fluorescent probe
    
  • 2z97, 2zaw, 2zax - PpP450cam+methyl depropionated hemin
    
  • 3cpp, 2lqd - PpP450cam+CO
    
  • 1pha, 1phb, 1phd, 1phe, 1phf, 1phg - PpP450cam+imidazole derivative
    
  • 1gek, 1gem - PpP450cam+N-butyl-isocyanide
    
  • 1lwl - PpP450cam+fluorescent probe
    
  • 2h7r - PpP450cam (mutant)+imidazole
    
  • 1k2o - PpP450cam (mutant)+pyridine derivative
    
  • 1gjm - PpP450cam (mutant)+sulphydryl reagent
    
  • 2a1m, 2a1n, 2a10 - PpP450cam (mutant)+ferrous dioxygen
    
  • 1t85, 1t86, 1t87, 1t88 - PpP450cam (mutant)+ferrous CO
    
  • 1j51 - PpP450cam (mutant)+trichlorobenzene
    
  • 1mpw - PpP450cam (mutant)+trimethylbicycloheptene
    
  • 3oia, 3ol5, 3p6m, 3p6n, 3p6o, 3p6p, 3poq, 3por, 3pos, 3pot, 3pou, 3pov, 3pow, 3pox, 3w9c, 5gxg - PpP450cam (mutant)+substrate analog
    
  • 4jws, 4jwu - PpP450cam (mutant)+ putidaredoxin
    
  • 4jx1, 6nbi - PpP450cam (mutant)+ putidaredoxin + camphor + hydroxycamphor
    
  • 4jx1 - PpP450cam (mutant)+ putidaredoxin + camphor + CN
    
  • 2m56 - PpP450cam + putidaredoxin + camphor
    
  • 3oft, 4c9m, 3lxh, 3lxi, 3ofu, 6hqw – NaP450 – Novosphignobium aromaticivorans
    
  • 4c9p - NaP450cam (mutant) + camphor
    
  • 4c9k - NaP450cam + camphor + hydroxycamphor
    
  • 4c9n, 6wgw - NaP450cam (mutant) + camphor + hydroxycamphor
    
  • 4c9l - NaP450cam + camphor + CN
    
  • 4c9o - NaP450cam (mutant) + camphor + CN
    
• P450nor or NADP nitrous oxide-forming nitric-oxide reductase or nitric oxide reductase
  • 1cl6, 1rom, 5y5j, 5y5l, 1jfb, 1jfc, 1ged, 1ehe – FoP450nor - Fusarium oxysporum
    
  • 2rom - FoP450nor+CO
    
  • 5y5f, 5y5g, 5y5h, 5y5k – FoP450nor + NO
    
  • 1f24, 1f25, 1f26 – FoP450nor (mutant) + NO
    
  • 5y5i – FoP450nor + NO + NADH
    
  • 1cmj, 1cmn, 1ehg, 1ehf, 1ulw - FoP450nor (mutant)
    
  • 1xqd – FoP450nor+pyridinealdehyde adenine
    
  • 1gej, 1gei - FoP450nor+N-butyl-isocyanide
    
• P450epoK
  • 1q5e - ScP450epoK - Sorangium cellulosum
    
  • 1q5d, 1pkf – ScP450epoK+epothilone
    
• P450cin
  • 3bdz, 3be0, 4fyz, 4fb2 – CbP450cin – Citrobacter braakii
    
  • 4lht, 4l77 - CbP450cin (mutant)
    
  • 4fmx, 1t2b – CbP450cin + cineole
    
  • 4l6g – CbP450cin (mutant) + cineole
    
• rabbit P450
  • 2bdm – rP450 CYP2B4 – rabbit
    
  • 1po5, 3mvr, 3r1a, 3r1b, 5iut, 5iuz, 5em4, 6bww - rP450 CYP2B4 (mutant)
    
  • 1suo,3g5n, 3g93, 2q6n, 3tk3 - rP450 CYP2B4 (mutant)+imidazole derivative
    
  • 4mgj - rP450 CYP2B4 (mutant)+ thiol derivative
    
  • 3kw4, 3me6, 3tmz, 4h1n - rP450 CYP2B4 (mutant)+anti-platelet drug
    
  • 4jlt - rP450 CYP CYP2B4 (mutant) + anti-depressant drug
    
  • 3uas - rP450 CYP CYP2B4 (mutant)+ inactivator
    
  • 5t6q - rP450 CYP4B1 + octane
    
  • 6c93 - rP450 CYP4B1 (mutant) + octane
    
  • 6c94 - rP450 CYP4B1 + inhibitor
    
  • 1dt6 - rP450 CYP2C5 (mutant)
    
  • 1nr6 – rP450 CYP2C5+diclofenac
    
  • 1n6b - rP450 CYP2C5+sulfaphenazole
• P450 BM3 or bifunctional P450/NADPH-P450 reductase; Domains – heme 1-458; FMN 459-647; FAD 659-1049
  • 3cbd, 2bmh, 2j4s, 4zfa, 1bu7 – BmP450 heme domain – Bacillus megaterium
    
  • 3dgi, 3hf2, 3kx3, 3kx4, 3kx5, 3m4v, 3npl, 3psx, 4dty, 4dua, 4duc, 4dud, 1jme, 1p0v, 1p0w, 1p0x, 1smi, 1yqp, 1yqo, 1zo4, 2nnb, 4hgj, 4h23, 4h24, 4kpb, 4kf0, 4kf2, 4wg2, 1fah, 4rsn, 4zf6, 5dyp, 5e7y, 5e9z, 5jqu, 5jqv, 5ucw - BmP450 heme domain (mutant)
    
  • 5zlh, 5zis - BmP450 heme domain + Mn-protoporphyrin
    
  • 4dtw, 4due, 4duf - BmP450 heme domain (mutant) + serotonin
    
  • 4dtz, 4du2, 4dub - BmP450 heme domain (mutant) + dopamine
    
  • 1jpz, 1zo9, 1zoa, 4kpa - BmP450 heme domain + palmitate derivative
    
  • 1smj, 5jq2 - BmP450 heme domain (mutant) + palmitate derivative
    
  • 2x7y, 2x80 - BmP450 heme domain (mutant) + DMSO
    
  • 6iao - BmP450 heme domain (mutant) + DTT
    
  • 4hgf, 4hgg, 4hgh, 4hgi - BmP450 heme domain (mutant) + styrene
    
  • 4kew, 4key, 4o4p, 4zf8, 6h1l, 6h1o, 6h1s, 6h1t, 6hn8 - BmP450 heme domain (mutant) + drug
    
  • 3ekb, 3ekd, 3ekf, 2ij3, 2ij4 - BmP450102 heme domain (mutant)
    
  • 2ij2, 2hpd - BmP450102 heme domain
    
  • 6jlv, 6jmh, 6jmw, 6js8, 6jvc, 6k24, 6k9s - BmP450102 heme domain + abietoyl-Trp
    
  • 6jzs - BmP450102 heme domain + abietoyl-Trp + pyridine
    
  • 6k3q, 6k58, 6jo1 - BmP450102 heme domain + Phe derivative
    
  • 4dqk - BmP450 FAD domain + FAD
    
  • 4dql - BmP450 FAD domain + NADP + FAD
    
  • 3wsp - BmP450 heme domain + decoy molecule
    
  • 2uwh - BmP450102+palmitic acid
    
  • 3ben, 7egn - BmP450 heme domain + inhibitor
    
  • 2j1m - BmP450102 heme domain +DMSO
    
  • 5jtd - BmP450102 heme domain (mutant) +DMSO
    
  • 1bvy – BmP450102A1 heme+FMN domains
    
  • 5e78 - BmP450 heme domain + Co + sepulchrate
    
  • 1fag – BmP450102A1 heme domain + palmitate
    
  • 4zfb, 5dyz - BmP450 (mutant) + palmitate
    
  • 5b2v, 5b2y, 5xa3, 5xhj - BmP450 heme domain + amino acid derivative
    
  • 5og9 - BmP450 heme domain + testosterone
    
  • 6ly4 - BmP450 heme domain (mutant) + testosterone
    
  • 5b2u, 5b2w, 5b2x - BmP450 heme domain (mutant) + tryptophan derivative
    
  • 7ckn, 7con, 7coo, 7cp8, 7cx8, 7d0t, 7d0u, 7d1f, 7e46, 7w97, 7w9d, 7w9j - PmP450 heme domain CYP102A1 + inhibitor
    
  • 4yt3 - BmP450 CYP106A2
    
  • 5iki - BmP450 CYP106A2 + abietic acid
    
  • 5l90 - BmP450 CYP109E1
    
  • 5l91, 5l92 - BmP450 CYP109E1 + corticosterone
    
  • 5l94 - BmP450 CYP109E1 + testosterone
    
  • 7f3h - P450 heme domain – Deinococcus aerius
    
  • 7f3w - P450 heme domain – Deinococcus apachensis
    
• Eukaryote P450 Cyp51 or lanosterol 14-alpha demethylase
  • 3juv – hCyp51
    
  • 3jus, 3ld6, 4uhi, 4uhl – hCyp51 + drug
    
  • 6uez – hCyp51 + lanosterol
    
  • 6q2t – hCyp51 + inhibitor
    
  • 5esi, 5esn – yCyp51 (mutant) - yeast
    
  • 5eab, 5eac, 5ead, 5eae, 5eaf, 5eag, 5eah, 7ryx, 8dl4 – yCyp51 + inhibitor
    
  • 4wmz, 5eqb, 5hs1, 5ul0, 6e8q, 7ryx – yCyp51 + drug
    
  • 4zdy, 4zdz, 4ze0, 4ze1, 4ze2, 4ze3, 5ese, 5esf, 5esg, 5esh, 5esj, 5esk, 5esl, 5esm, 7ry8, 7ry9, 7rya, 7ryb – yCyp51 (mutant) + drug
    
  • 4lxj – yCyp51 + lanosterol
    
  • 5v5z – CaP450 CYP51 – Candida albicans
    
  • 5tz1 – CaP450 CYP51 + drug
    
  • 5fsa – CaP450 CYP51 (mutant) + drug
    
• Bacterial P450 Cyp51 or lanosterol 14-alpha demethylase
  • 6mi0, 7jj1– McP450 CYP51 – Methylcoccus capsulatus
    
  • 7tef – MmP450 CYP51B1 – Mycobacterium marinum
    
  • 3g1q – TbP450 CYP51 – Trypanosoma brucei
    
  • 5jlc – P450 CYP51 – Candida glabrata
    
  • 4bmm, 4by0, 4c0c, 4c27, 4c28, 4coh, 4uqh, 4uvr – P450 CYP51 + inhibitor – Trypanosoma cruzi
    
  • 6fmo – P450 CYP51 (mutant) + obtosifoliol
    
  • 6mcw – McP450 CYP51 + detergent
    
  • 7snm – McP450 CYP51 + drug
    
  • 7rkr – NfP450 CYP51 + inhibitor
    
  • 2wv2, 2wx2, 2x2n, 3tik – TbP450 CYP51 + drug
    
  • 3gw9, 4bjk, 4g3j, 4g7g – TbP450 CYP51 + inhibitor
    
  • 3p99 – TbP450 CYP51 + lanosterol derivative
    
  • 6ay4, 6ayb, 6ayc – NfP450 CYP51 + drug – Naegleria fowleri
    
  • 3l4d – P450 CYP51 + drug – Leishmania infantum
    
• Other CYPs
  • 1ued – AoP450 oxyC – Amycolatopsis orientalis
    
  • 1lfk, 1lg9, 1lgf - AoP450 oxyB
    
  • 5ex6, 5ex9, 5ex8 - P450 – Streptomyces toyocaensis
    
  • 5vws - P450 – Thermobispora bispora
    
  • 3p3l, 3p3o, 3p3x, 3p3z – P450 – Streptomyces thioluteus
    
  • 2rfb – PtP450 – Picrophilus torridus
    
  • 6gii, 6laa – P450 – Tepidiphilus thermophilus
    
  • 1wiy – TtP450 – Thermus thermophilus
    
  • 4e2p, 5xw2 - P450 – Streptococcus himastatinicus
    
  • 6g5q, 6g5o - P450 – Zobellia galactanivorans
    
  • 5ysm – AmP450 – Amycolatopsis mediterranei
    
  • 6f0c, 6f0b - P450 TXTC – Streptomyces acidiscabies
    
  • 5gwe, 7ccf – CgP450 CreJ – Corynebacterium glutamicum
    
  • 5y1i - P450 GFSF – Streptomyces graminofaciens
    
  • 1cpt – PsP450 TERP - Pseudomonas sp.
    
  • 4l0e, 4l0f - StP450 SKY32– Streptomyces
    
  • 3awp, 3awq - SpP450-α (mutant) - Sphingomonas paucimobilis
    
  • 3a4g, 3a4h – PaP450 VDH – Pseudonocardia autotrophica
    
  • 3a4z, 5gnm, 5gnl - PaP450 VDH (mutant)
    
  • 3qi8 – P450 – synthetic
    
  • 3g1q – TbP450 CYP51 – Trypanosoma brucei
    
  • 3dam, 3dan, 3dbm – P45074A2 – Parthenium argentatum
    
  • 2rcm, 3cli - AtP45074A - Arabidopsis thaliana
    
  • 6j94 - AtP450 CYP97A3
    
  • 6l8i - AtP450 CYP97A3 (mutant)
    
  • 5kyo - P450 CYP101J2 – Sphingobium yanoikuyae
    
  • 3nv5, 3nv6, 4dxy - NaP450 CYP101D2
    
  • 6n6q - P450 CYP102L1 – Mycobacterium phage adler
    
  • 4oqs - AoP450 CYP105AS1
    
  • 3abb – SaP450 CYP105D6 - Streptomyces avermitilis
    
  • 3e5j, 3e5l - SaP450 CYP105P1 (mutant)
    
  • 2z3u - SgP450 CYP105A1 (mutant) – Streptomyces griseolus
    
  • 5xnt - P450 CYP106A2 – Bacillus butanolivorans
    
  • 6l39 - SrP450 CYP107G1 – Streptomyces rapamycinicus
    
  • 4wpz - SaP450 CYP107W1
    
  • 2whw, 2wi9, 2vz7 – SvP450107L1 (mutant) – Streptomyces venezuelae
    
  • 2bvj - SvP450107L1
    
  • 3tkt – NaP450 CYP108D1
    
  • 5ofq - BmP450 CYP109A2
    
  • 4rm4 - BsP450 CYP109B1
    
  • 2jjn, 2jjo - SeP450 CYP113A1 (mutant) - Saccharopolyspora erythraea
    
  • 6ro8 - P450 CYP116B5 – Acinetobacter radioresistens
    
  • 1io8, 5bv5 – SsP450 CYP119 (mutant) – Sulfolobus solfataricus
    
  • 1io9, 1io7, 1f4u - SsP450 CYP119
    
  • 6cvc – MmP450 CYP124A1
    
  • 5dqn - MsP450 CYP125A3 (mutant) – Mycobacterium smegmatis
    
  • 3nc3, 3nc5, 3nc6, 3nc7 - BsP450 CYP134A1 (mutant)
    
  • 7tlo – MmP450 CYP142A3
    
  • 2zqj – BsP450152A1 – Bacillus subtilis
    
  • 5fyf - MhP450 CYP153A – Marinobacter hydrocarbonoclasticus
    
  • 6hqg - P450 CYP153 – Phenylobacterium zucineum
    
  • 6hqd – PsP450 CYP153
    
  • 7ant – PoP450 CYP153 - Polaromonas
    
  • 1gwi - ScP450 CYP154C1
    
  • 6a7i - SvP450 CYP154C4 – Streptomyces violaceruber
    
  • 2nz5, 2nza, 2dkk – ScP450 CYP158A1 – Streptomyces coelicolor
    
  • 3r9b – MsP450 CYP164A2
    
  • 6dcd – MmP450 CYP164A6
    
  • 3o1a – P450 CYP165D3 – Actinoplanes teichomyceticus
    
  • 1n97 – TtP450 CYP175A1
    
  • 4dnz – RpP450 CYP199A4 – Rhodopseudomonas palustris
    
  • 2z3t - StrP450 CYP245A1
    
  • 5liv - ScP450 CYP260A1
    
  • 6f85 - ScP450 CYP260A1 (mutant)
    
  • 5hiw - ScP450 CYP260B1
    
  • 6gk5 - ScP450 CYP267B1
    
  • 6g71 - P450 CYP1232A24 - Arthrobacter
    
  • 6m4q - SspP450 – Streptomyces spectabilis
    
  • 6j82 - SbP450 TleB – Streptomyces blastmyceticus
    
  • 7ayx - P450 AryC – Streptomyces filamentosus
    
  • 7oq6 - P450 Sas16 – Streptomyces calvus
    
  • 6kbh – ReP450 – Rhodococcus erythropolis
    
  • 7v40 – RcP450 – Rhodococcus coprophilus
    
  • 6zhz - SanP450 – Streptomyces antibioticus
    
  • 7qan - P450 – Micromonospora maris
    
• Other CYPs complexes
  • 2rfc – PtP450+phenylimidazole
    
  • 3wec – ReP450 + dihydroxy-aurachin Re
    
  • 5ysw – AmP450+ rifamycin
    
  • 5omu – AmP450+ syringol
    
  • 5oms – AmP450+ guaethol
    
  • 5ncb – AmP450+ guaiacol
    
  • 5omr – AmP450+ vanilin
    
  • 6hqk, 6hql. 6hqm, 6hqn, 6hqo, 6hqp – AoP450 (mutant) + guaiacol
    
  • 6hqs – AoP450 + syringol
    
  • 6hqq, 6hqr, 6hqt – AoP450 (mutant) + syringol
    
  • 4pwv, 4pxh - StP450 SKY32 + peptidyl carrier protein domain
    
  • 2zqx - BsP450 BS b +heptanoic acid
    
  • 1izo – BsP450 BS beta+ palmitoleic acid
    
  • 3awm – SpP450-α + palmitic acid
    
  • 3a50, 3a51 - PaP450 VDH (mutant) + vitamin D3
    
  • 5xjn – CgP450 CREJ + ethylphenyl derivative
    
  • 2rch, 3dsi – AtP450 CYP74A+13(S)-HOD
    
  • 3dsj - AtP450 CYP74A (mutant)+13(S)-HOD
    
  • 2rcl - AtP450 CYP74A+vernolic acid
    
  • 7p6l - P450 CYP505A30 + dodecanoic acid – Mycelyophthora thermophila
    
  • 3dsk - AtP450 CYP74A (mutant)+ vernolic acid
    
  • 6a15 - AtP450 CYP90B1 (mutant) + cholesterol
    
  • 6a16 - AtP450 CYP90B1 (mutant) + uniconazole
    
  • 6a17 - AtP450 CYP90B1 (mutant) + brassinazole
    
  • 6a18 - AtP450 CYP90B1 (mutant) + hexanediol
    
  • 6j94 - AtP450 CYP97A3 + retinal
    
  • 6l8j - AtP450 CYP97A3 (mutant) + retinal
    
  • 3cv9, 2zbz - SgP450 CYP105A1 (mutant)+vitamin D3
    
  • 2zbx - SgP450 CYP105A1+imidazole
    
  • 5x7e - SgP450 CYP105A1 (mutant)+vitamin D2<br /
  • 3aba – SaP450 CYP105P1+filipin I
    
  • 3e5k - SaP450 CYP105P1 (mutant)+4-phenylimidazole
    
  • 4oqr - AoP450 CYP105AS1 (mutant) + compactin
    
  • 7q9e - PmP450 CYP106A1 – Priestia megaterium
    
  • 7cvr, 7cx6, 7czi - PmP450 CYP106A1 + inhibitor
    
  • 1jin, 1jip - SeP450 CYP107A1+ ketoconazole
    
  • 1jio, 1oxa - SeP450 CYP107A1+6DEB
    
  • 1eup – SeP450 CYP107A1+androstendione
    
  • 1egy - SeP450 CYP107A1+aminophenanthrene
    
  • 6kzs - SgP450 CYP107F1 + imidazole
    
  • 6l3a - SrP450 CYP107G1 + drug
    
  • 4wq0 - SaP450 CYP107W1 + oligomycin
    
  • 2vzm – SvP450 CYP107L1 (mutant)+narbomycin
    
  • 2c7x - SvP450 CYP107L1+narbomycin
    
  • 2cd8, 2ca0, 2c6h – SvP450 CYP107L1+YC-17
    
  • 4tt5, 4tuv, 4wpd, 4wqj - P450 CYP119+ imidazole derivative – Sulfolobus acidocaldarius
    
  • 7smz – MmP450 CYP142A3 + cholestenone
    
  • 5yhj - P450 CYP152N1 + myristic acid - Exiguobacterium
    
  • 5fyg - MhP450 CYP153A + dodecanoic acid
    
  • 7ao7 – PoP450 CYP153 + octanol
    
  • 6to2 - NfP450 CYP154C4 + androstan derivative – Nocardia farcinica
    
  • 4j6b, 4jbc, 4jbd, 4jbt - NfP450 CYP154C5 + hormone
    
  • 6a7j - SvP450 CYP154C4 + testosterone
    
  • 3r9c – MsP450 CYP164A2 + econazole
    
  • 4do1, 4egm, 6c3j, 6c3h, 6c2d, 5yqh, 5yqa, 5uvb, 5u6w, 5u6u, 5u6t, 5kt1, 5kdb, 6oow, 6pq6, 6pqd, 6pqs, 6pqw, 6prr, 6prs, 6u30, 6u31, 6u3k, 7jw5, 7jxb, 7kcs, 7n14, 7r8s, 7r8t, 7reh – RpP450 CYP199A4 + benzoate derivative
    
  • 5kdz, 5kdy, 6oox , 7n60– RpP450 CYP199A4 (mutant) + benzoate derivative
    
  • 4egn – RpP450 CYP199A4 + veratric acid
    
  • 4egp – RpP450 CYP199A4 + naphthoic acid
    
  • 6unn – RpP450 CYP199A4 + cinnamic acid derivative
    
  • 4ego – RpP450 CYP199A4 + indole derivative
    
  • 3a1l – StrP450 CYP245A1+dichlorochrompyrrolic acid
    
  • 6f88, 6f8c - ScP450 CYP260A1 (mutant) + progesterone
    
  • 6f8a - ScP450 CYP260A1 (mutant) + histidine
    
  • 6gk6 - ScP450 CYP267B1 + myristic acid
    
  • 6bld - MmP450 CYP268A2 + pseudoionone
    
  • 4r20 - zP450 17A2 + abiraterone – zebra fish
    
  • 6b82 - zP450 17A1 (mutant) + abiraterone
    
  • 4r21 - zP450 17A2 + progesterone
    
  • 6m4p - SspP450 + antibiotic
    
  • 6zi3, 7zi7 - SanP450 + rhamnose
    
  • 7q6x - SanP450 + erythronolide
    
  • 7q6r, 7q89 - SanP450 (mutant) + erythronolide
    
  • 6j84 - SbP450 TleB + hydroxyl analog
    
  • 6j83 - SbP450 TleB + NMVT
    
  • 7v41, 7v45, 7v46 – RcP450 + toluene derivative
    

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Openfox