Cytochrome P450 3D structures: Difference between revisions

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**[[3ua1]] - hP4503A4 + ergocryptine<br />
**[[3ua1]] - hP4503A4 + ergocryptine<br />
**[[5vcg]] - hP4503A4 (mutant) + ergocryptine<br />
**[[5vcg]] - hP4503A4 (mutant) + ergocryptine<br />
**[[4ny4]], [[4d7d]], [[4d78]], [[4d75]], [[4d6z]], [[6bdm]], [[6bdk]], [[6bdi]], [[6bdh]], [[6bd8]], [[6bd7]], [[6bd6]], [[6bd5]], [[6bcz]], [[6ma8]], [[6ma7]], [[6ma6]], [[6dal]], [[6daj]], [[6dag]], [[6dac]], [[6dab]], [[6daa]], [[6da8]], [[6da5]], [[6da3]], [[6da2]], [[6une]], [[6ung]], [[6unh]], [[6uni]], [[6unj]], [[6unk]], [[6unl]], [[6unm]] - hP4503A4 + inhibitor <br />
**[[4ny4]], [[4d7d]], [[4d78]], [[4d75]], [[4d6z]], [[6bdm]], [[6bdk]], [[6bdi]], [[6bdh]], [[6bd8]], [[6bd7]], [[6bd6]], [[6bd5]], [[6bcz]], [[6ma8]], [[6ma7]], [[6ma6]], [[6dal]], [[6daj]], [[6dag]], [[6dac]], [[6dab]], [[6daa]], [[6da8]], [[6da5]], [[6da3]], [[6da2]], [[6une]], [[6ung]], [[6unh]], [[6uni]], [[6unj]], [[6unk]], [[6unl]], [[6unm]], [[7ks8]], [[7ksh]], [[7kvh]], [[7kvi]], [[7kvj]], [[7kvn]], [[7kvo]], [[7kvs]] - hP4503A4 + inhibitor <br />
**[[5te8]] - hP4503A4 + sedation drug <br />
**[[5te8]] - hP4503A4 + sedation drug <br />
**[[5a1p]], [[5a1r]] - hP4503A4 + progesterone <br />
**[[5a1p]], [[5a1r]] - hP4503A4 + progesterone <br />
**[[7lxl]] - hP4503A4 + testosterone <br />
**[[6mjm]] - hP4503A5 <br />
**[[6mjm]] - hP4503A5 <br />
**[[5veu]] - hP4503A5 + inhibitor<br />
**[[5veu]] - hP4503A5 + inhibitor<br />
Line 98: Line 99:
* human P450 17 A1 family (steroid 17-α-hydroxylase 17,20 lyase)
* human P450 17 A1 family (steroid 17-α-hydroxylase 17,20 lyase)


**[[5uys]], [[3ruk]], [[6chi]], [[6cir]], [[6ciz]] - hP450 C17 + abiraterone derivative<br />
**[[5uys]], [[3ruk]], [[6chi]], [[6cir]], [[6ciz]], [[6wr0]], [[6ww0]] - hP450 C17 + abiraterone derivative<br />
**[[4nkv]] - hP450 C17 (mutant) + abiraterone derivative<br />
**[[4nkv]], [[6wr1]] - hP450 C17 (mutant) + abiraterone derivative<br />
**[[5irq]] - hP450 C17 + orteronel<br />
**[[5irq]] - hP450 C17 + orteronel<br />
**[[5irv]] - hP450 C17 + inhibitor<br />
**[[5irv]] - hP450 C17 + inhibitor<br />
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* P450cam or camphor-5 momooxygenase
* P450cam or camphor-5 momooxygenase


**[[1dz4]], [[1dz8]], [[1dz6]], [[1dz9]], [[5cp4]], [[1phc]], [[2cpp]], [[1yrc]], [[1yrd]], [[3l61]], [[3l62]], [[3l63]], [[3wrh]], [[3wri]], [[3wrk]] - PpP450cam - ''Pseudomona putida''<br />
**[[1dz4]], [[1dz8]], [[1dz6]], [[1dz9]], [[5cp4]], [[1phc]], [[2cpp]], [[1yrc]], [[1yrd]], [[3l61]], [[3l62]], [[3l63]], [[3wrh]], [[3wri]], [[3wrk]], [[6wpl]] - PpP450cam - ''Pseudomona putida''<br />
**[[2qbl]], [[2qbm]], [[2qbn]], [[2gqx]], [[2gr6]], [[2frz]], [[2h7s]], [[6cp4]], [[2cp4]], [[3cp4]], [[4cp4]], [[1c8j]], [[1geb]], [[2a1o]], [[3p6q]], [[3p6r]], [[3p6s]], [[3p6t]], [[3p6u]], [[3p6v]], [[3p6w]], [[3p6x]], [[4ek1]], [[5wk7]], [[6we6]], [[6wfl]] – PpP450cam (mutant) <br />
**[[2qbl]], [[2qbm]], [[2qbn]], [[2gqx]], [[2gr6]], [[2frz]], [[2h7s]], [[6cp4]], [[2cp4]], [[3cp4]], [[4cp4]], [[1c8j]], [[1geb]], [[2a1o]], [[3p6q]], [[3p6r]], [[3p6s]], [[3p6t]], [[3p6u]], [[3p6v]], [[3p6w]], [[3p6x]], [[4ek1]], [[5wk7]], [[6we6]], [[6wfl]] – PpP450cam (mutant) <br />
**[[2qbo]] - PpP450cam (mutant)+cyanide<br />
**[[2qbo]] - PpP450cam (mutant)+cyanide<br />
Line 278: Line 279:
**[[3p3l]], [[3p3o]], [[3p3x]], [[3p3z]] – P450 – ''Streptomyces thioluteus''<br />
**[[3p3l]], [[3p3o]], [[3p3x]], [[3p3z]] – P450 – ''Streptomyces thioluteus''<br />
**[[2rfb]] – PtP450 – ''Picrophilus torridus''<br />
**[[2rfb]] – PtP450 – ''Picrophilus torridus''<br />
**[[6gii]] – P450 – ''Tepidiphilus thermophilus''<br />
**[[6gii]], [[6laa]] – P450 – ''Tepidiphilus thermophilus''<br />
**[[1wiy]] – TtP450 – ''Thermus thermophilus''<br />
**[[1wiy]] – TtP450 – ''Thermus thermophilus''<br />
**[[4e2p]], [[5xw2]] - P450 – ''Streptococcus himastatinicus''<br />
**[[4e2p]], [[5xw2]] - P450 – ''Streptococcus himastatinicus''<br />
Line 284: Line 285:
**[[5ysm]] – AmP450 – ''Amycolatopsis mediterranei''<br />
**[[5ysm]] – AmP450 – ''Amycolatopsis mediterranei''<br />
**[[6f0c]], [[6f0b]] - P450 TXTC – ''Streptomyces acidiscabies''<br />
**[[6f0c]], [[6f0b]] - P450 TXTC – ''Streptomyces acidiscabies''<br />
**[[5gwe]] – CgP450 CREJ – ''Corynebacterium glutamicum''<br />
**[[5gwe]], [[7ccf]] – CgP450 CreJ – ''Corynebacterium glutamicum''<br />
**[[5y1i]] - P450 GFSF – ''Streptomyces graminofaciens''<br />
**[[5y1i]] - P450 GFSF – ''Streptomyces graminofaciens''<br />
**[[1cpt]] – PsP450 TERP - ''Pseudomonas sp.''<br />
**[[1cpt]] – PsP450 TERP - ''Pseudomonas sp.''<br />
Line 293: Line 294:
**[[3qi8]] – P450 – synthetic<br />
**[[3qi8]] – P450 – synthetic<br />
**[[6mi0]] – McP450 CYP51 – ''Methylcoccus capsulatus''<br />
**[[6mi0]] – McP450 CYP51 – ''Methylcoccus capsulatus''<br />
**[[6ay4]], [[6ayb]], [[6ayc]] – P450 CYP51 + drug – ''Naegleria fowleri''<br />
**[[3dam]], [[3dan]], [[3dbm]] – P45074A2 – ''Parthenium argentatum''<br />
**[[3dam]], [[3dan]], [[3dbm]] – P45074A2 – ''Parthenium argentatum''<br />
**[[2rcm]], [[3cli]] - AtP45074A - ''Arabidopsis thaliana''<br />
**[[2rcm]], [[3cli]] - AtP45074A - ''Arabidopsis thaliana''<br />
Line 303: Line 305:
**[[3abb]] – SaP450 CYP105D6 - ''Streptomyces avermitilis''<br />
**[[3abb]] – SaP450 CYP105D6 - ''Streptomyces avermitilis''<br />
**[[3e5j]], [[3e5l]] - SaP450 CYP105P1 (mutant)<br />
**[[3e5j]], [[3e5l]] - SaP450 CYP105P1 (mutant)<br />
**[[2z3u]] - SsP450 CYP105A1 (mutant) – ''Streptomyces griseolus''<br />
**[[2z3u]] - SgP450 CYP105A1 (mutant) – ''Streptomyces griseolus''<br />
**[[5xnt]] - P450 CYP106A2 – ''Bacillus butanolivorans''<br />
**[[5xnt]] - P450 CYP106A2 – ''Bacillus butanolivorans''<br />
**[[6l39]] - SrP450 CYP107G1 – ''Streptomyces rapamycinicus''<br />
**[[4wpz]] - SaP450 CYP107W1 <br />
**[[4wpz]] - SaP450 CYP107W1 <br />
**[[2whw]], [[2wi9]], [[2vz7]] – SvP450107L1 (mutant) – ''Streptomyces venezuelae''<br />
**[[2whw]], [[2wi9]], [[2vz7]] – SvP450107L1 (mutant) – ''Streptomyces venezuelae''<br />
Line 322: Line 325:
**[[6hqg]] - P450 CYP153 – ''Phenylobacterium zucineum''<br />
**[[6hqg]] - P450 CYP153 – ''Phenylobacterium zucineum''<br />
**[[6hqd]] – PsP450 CYP153 <br />
**[[6hqd]] – PsP450 CYP153 <br />
**[[7ant]] – PoP450 CYP153 - ''Polaromonas''<br />
**[[1gwi]] - ScP450 CYP154C1<br />
**[[1gwi]] - ScP450 CYP154C1<br />
**[[6a7i]] - SvP450 CYP154C4 – ''Streptomyces violaceruber''<br />
**[[6a7i]] - SvP450 CYP154C4 – ''Streptomyces violaceruber''<br />
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**[[6gk5]] - ScP450 CYP267B1 <br />
**[[6gk5]] - ScP450 CYP267B1 <br />
**[[6g71]] - P450 CYP1232A24 - ''Arthrobacter''<br />
**[[6g71]] - P450 CYP1232A24 - ''Arthrobacter''<br />
**[[6m4q]] - SspP450 – ''Streptomyces spectabilis''<br />
**[[6j82]] - SbP450 TleB – ''Streptomyces blastmyceticus''<br />
**[[6kbh]] – ReP450 – ''Rhodococcus erythropolis''<br />


*Other CYPs complexes
*Other CYPs complexes


**[[2rfc]] – PtP450+phenylimidazole<br />
**[[2rfc]] – PtP450+phenylimidazole<br />
**[[3wec]] – P450 + dihydroxy-aurachin Re – ''Rhodococcus erythropolis''<br />
**[[3wec]] – ReP450 + dihydroxy-aurachin Re <br />
**[[5ysw]] – AmP450+ rifamycin <br />
**[[5ysw]] – AmP450+ rifamycin <br />
**[[5omu]] – AmP450+ syringol <br />
**[[5omu]] – AmP450+ syringol <br />
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**[[3cv9]], [[2zbz]] - SgP450 CYP105A1 (mutant)+vitamin D3<br />
**[[3cv9]], [[2zbz]] - SgP450 CYP105A1 (mutant)+vitamin D3<br />
**[[2zbx]] - SgP450 CYP105A1+imidazole<br />
**[[2zbx]] - SgP450 CYP105A1+imidazole<br />
**[[5x7e]] - SsP450 CYP105A1 (mutant)+vitamin D2<br /
**[[5x7e]] - SgP450 CYP105A1 (mutant)+vitamin D2<br /
**[[3aba]] – SaP450 CYP105P1+filipin I <br />
**[[3aba]] – SaP450 CYP105P1+filipin I <br />
**[[3e5k]] - SaP450 CYP105P1 (mutant)+4-phenylimidazole<br />
**[[3e5k]] - SaP450 CYP105P1 (mutant)+4-phenylimidazole<br />
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**[[1eup]] – SeP450 CYP107A1+androstendione<br />
**[[1eup]] – SeP450 CYP107A1+androstendione<br />
**[[1egy]] - SeP450 CYP107A1+aminophenanthrene<br />
**[[1egy]] - SeP450 CYP107A1+aminophenanthrene<br />
**[[6kzs]] - SgP450 CYP107F1 + imidazole<br />
**[[6l3a]] - SrP450 CYP107G1 + drug<br />
**[[4wq0]] - SaP450 CYP107W1 + oligomycin<br />
**[[4wq0]] - SaP450 CYP107W1 + oligomycin<br />
**[[2vzm]] – SvP450 CYP107L1 (mutant)+narbomycin<br />
**[[2vzm]] – SvP450 CYP107L1 (mutant)+narbomycin<br />
Line 388: Line 397:
**[[5yhj]] - P450 CYP152N1 + myristic acid - ''Exiguobacterium''<br />
**[[5yhj]] - P450 CYP152N1 + myristic acid - ''Exiguobacterium''<br />
**[[5fyg]] - MhP450 CYP153A + dodecanoic acid<br />
**[[5fyg]] - MhP450 CYP153A + dodecanoic acid<br />
**[[7ao7]] – PoP450 CYP153 + octanol <br />
**[[6to2]] - NfP450 CYP154C4 + androstan derivative – ''Nocardia farcinica'' <br />
**[[4j6b]], [[4jbc]], [[4jbd]], [[4jbt]] - NfP450 CYP154C5 + hormone<br />
**[[6a7j]] - SvP450 CYP154C4 + testosterone <br />
**[[6a7j]] - SvP450 CYP154C4 + testosterone <br />
**[[3r9c]] – MsP450 CYP164A2 + econazole<br />
**[[3r9c]] – MsP450 CYP164A2 + econazole<br />
**[[4do1]], [[4egm]], [[6c3j]], [[6c3h]], [[6c2d]], [[5yqh]], [[5yqa]], [[5uvb]], [[5u6w]], [[5u6u]], [[5u6t]], [[5kt1]], [[5kdb]], [[6oow]], [[6pq6]], [[6pqd]], [[6pqs]], [[6pqw]], [[6prr]], [[6prs]], [[6u30]], [[6u3k]] – RpP450 CYP199A4 + benzoate derivative<br />
**[[4do1]], [[4egm]], [[6c3j]], [[6c3h]], [[6c2d]], [[5yqh]], [[5yqa]], [[5uvb]], [[5u6w]], [[5u6u]], [[5u6t]], [[5kt1]], [[5kdb]], [[6oow]], [[6pq6]], [[6pqd]], [[6pqs]], [[6pqw]], [[6prr]], [[6prs]], [[6u30]], [[6u31]], [[6u3k]] – RpP450 CYP199A4 + benzoate derivative<br />
**[[5kdz]], [[5kdy]], [[6oox]] – RpP450 CYP199A4 (mutant) + benzoate derivative<br />
**[[5kdz]], [[5kdy]], [[6oox]] – RpP450 CYP199A4 (mutant) + benzoate derivative<br />
**[[4egn]] – RpP450 CYP199A4 + veratric acid<br />
**[[4egn]] – RpP450 CYP199A4 + veratric acid<br />
**[[4egp]] – RpP450 CYP199A4 + naphthoic acid<br />
**[[4egp]] – RpP450 CYP199A4 + naphthoic acid<br />
**[[46unn]] – RpP450 CYP199A4 + cinnamic acid derivative<br />
**[[4ego]] – RpP450 CYP199A4 + indole derivative<br />
**[[4ego]] – RpP450 CYP199A4 + indole derivative<br />
**[[3a1l]] – StrP450 CYP245A1+dichlorochrompyrrolic acid <br />
**[[3a1l]] – StrP450 CYP245A1+dichlorochrompyrrolic acid <br />
Line 402: Line 415:
**[[4r20]] - zP450 17A2 + abiraterone – zebra fish<br />
**[[4r20]] - zP450 17A2 + abiraterone – zebra fish<br />
**[[6b82]] - zP450 17A1 (mutant) + abiraterone <br />
**[[6b82]] - zP450 17A1 (mutant) + abiraterone <br />
**[[6m4p]] - SspP450 + antibiotic <br />
**[[6zi3]] - P450 + rhamnose – ''Streptomyces antibioticus''<br />
**[[6j84]] - SbP450 TleB + hydroxyl analog<br />
**[[6j83]] - SbP450 TleB + NMVT<br />


}}
}}


[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 09:28, 22 June 2021

3D Structures of Cytochrome P450

Updated on 22-June-2021

    • 2hi4 – hP4501A2+naphthoflavone - human
    • 4i8v - hP4501A1 +naphthoflavone
    • 6dwn - hP4501A1 + erlotinib
    • 6dwm - hP4501A1 + bergamottin
    • 3pm0, 6oyu - hP4501B1+naphthoflavone
    • 6iq5, 6o5y - hP4501B1 + inhibitor
    • 6oyv - P4501B1 + estradiol - synthetic
  • human P450 2 family
  • human P450 2 family complex
    • 3ebs – hP4502A6 (mutant)+phenacetin
    • 2fdu, 2fdv, 2fdw, 2fdy - hP4502A6+pyridine derivative
    • 1z10 - hP4502A6 catalytic domain+coumarin
    • 4ejj - hP4502A6 + nicotine
    • 3t3q, 3t3r - hP4502A6 (mutant) + pilocarpine
    • 2z10 – hP4502A6+coumarin
    • 1z11 - hP4502A6+methoxalen
    • 4rui – hP450 2A6 + volatile hydrocarbon
    • 3t3s - hP4502A13 + pilocarpine
    • 4ejg - hP4502A13 + nicotine
    • 4ejh, 4eji - hP4502A13 + pyridine derivative
    • 2p85 – hP4502A13 (mutant)+indole
    • 3ibd – hP4502B6 (mutant)+4-(4-chlorophenyl)imidazole
    • 3ua5 – hP4502B6 (mutant) + amlodipine
    • 4i91, 4zv8 - hP4502B6 (mutant) + pinine
    • 5wbg - hP4502B6 (mutant) + HIV drug
    • 3qoa, 2qu8, 3qu8 – hP450 2B6 (mutant) + inhibitor
    • 4rql, 4rrt – hP450 2B6 (mutant) + volatile hydrocarbon
    • 5ufg, 5uec, 5uap – hP450 2B6 (mutant) + Br derivative
    • 5uda – hP450 2B6 (mutant) + monoterpene borane
    • 5e58 – dwP450 2B35 + inhibitor – desert woodrat
    • 5e0e – dwP450 2B37 + inhibitor
    • 2nnh – hP4502C8+retinoic acid
    • 2nni - hP4502C8+montelukast
    • 2nnj - hP4502C8+felodipine
    • 1r9o – hP4502C9 (mutant)+flurbiprofen
    • 5xxi, 5x23, 5x24 - hP4502C9 (mutant) + blood pressure drug
    • 5a5i, 5a5j, 5w0c, 5k7k - hP4502C9 + inhibitor
    • 4nz2 - hP4502C9 (mutant) + inhibitor
    • 3tbg, 4wnw – hP4502D6 + thioridazine
    • 6csb - hP4502D6 (mutant) + thioridazine
    • 3tda – hP4502D6 + prinomastat
    • 6csd - hP4502D6 (mutant) + prinomastat
    • 4wnt - hP4502D6 + ajmalicine
    • 4wnu, 4wnv - hP4502D6 + quinine derivative
    • 5tft, 5tfu, 4xry, 4xrz - hP4502D6 + Bace1 inhibitor
    • 3gph, 3koh, 3lc4 – hP4502E1 fragment +imidazole derivative
    • 3e6i – hP4502E1 fragment+indazole
    • 3e4e – hP4502E1 fragment+methylpyrazole
    • 3t3z - hP4502E1 + pilocarpine
    • 3czh, 3dl9, 3c6g – hP4502R1+vitamin D
  • human P450 3 family
  • human P450 7 family
    • 3dax – hP4507A1
    • 3sn5 - hP4507A1 + cholest-4-en-3-one
  • human P450 11 family
    • 6m7x - hP450 CYP11B1 + fadrozole
    • 4dvq - hP450 CYP11B2 + corticosterone
    • 4fdh - hP450 CYP11B2 + fadrozole
    • 4zgx, 6xz8, 6xz9 - hP450 CYP11B2 + inhibitor
  • human P450 17 A1 family (steroid 17-α-hydroxylase 17,20 lyase)
    • 5uys, 3ruk, 6chi, 6cir, 6ciz, 6wr0, 6ww0 - hP450 C17 + abiraterone derivative
    • 4nkv, 6wr1 - hP450 C17 (mutant) + abiraterone derivative
    • 5irq - hP450 C17 + orteronel
    • 5irv - hP450 C17 + inhibitor
    • 4nkw, 4nkz - hP450 C17 (mutant) + pregnenolone derivative
    • 4nkx, 4nky - hP450 C17 (mutant) + progesterone derivative
    • 3swz - hP450 C17 + drug
  • human P450 19 family (aromatase)
  • human P450 46 family
    • 2q9f – hP45046A1+cholesterol
    • 2q9d, 2q9g - hP45046A1
    • 2vn0 – hP450105A1+troglitazone
    • 2zby - hP450105A1 (mutant)
  • P450 from Mycobacterium tuberculosis or sterol 14-α demethylase
  • P450cam or camphor-5 momooxygenase
  • P450nor or NADP nitrous oxide-forming nitric-oxide reductase or nitric oxide reductase
  • P450epoK
    • 1q5e - ScP450epoK - Sorangium cellulosum
    • 1q5d, 1pkf – ScP450epoK+epothilone
  • P450cin
  • rabbit P450
    • 2bdm – rP450 CYP2B4 – rabbit
    • 1po5, 3mvr, 3r1a, 3r1b, 5iut, 5iuz, 5em4, 6bww - rP450 CYP2B4 (mutant)
    • 1suo,3g5n, 3g93, 2q6n, 3tk3 - rP450 CYP2B4 (mutant)+imidazole derivative
    • 4mgj - rP450 CYP2B4 (mutant)+ thiol derivative
    • 3kw4, 3me6, 3tmz, 4h1n - rP450 CYP2B4 (mutant)+anti-platelet drug
    • 4jlt - rP450 CYP CYP2B4 (mutant) + anti-depressant drug
    • 3uas - rP450 CYP CYP2B4 (mutant)+ inactivator
    • 5t6q - rP450 CYP4B1 + octane
    • 6c93 - rP450 CYP4B1 (mutant) + octane
    • 6c94 - rP450 CYP4B1 + inhibitor
    • 1dt6 - rP450 CYP2C5 (mutant)
    • 1nr6 – rP450 CYP2C5+diclofenac
    • 1n6b - rP450 CYP2C5+sulfaphenazole
  • P450 BM3 or bifunctional P450/NADPH-P450 reductase; Domains – heme 1-458; FMN 459-647; FAD 659-1049
  • Other CYPs
    • 1ued – AoP450 oxyC – Amycolatopsis orientalis
    • 1lfk, 1lg9, 1lgf - AoP450 oxyB
    • 5ex6, 5ex9, 5ex8 - P450 – Streptomyces toyocaensis
    • 5vws - P450 – Thermobispora bispora
    • 3p3l, 3p3o, 3p3x, 3p3z – P450 – Streptomyces thioluteus
    • 2rfb – PtP450 – Picrophilus torridus
    • 6gii, 6laa – P450 – Tepidiphilus thermophilus
    • 1wiy – TtP450 – Thermus thermophilus
    • 4e2p, 5xw2 - P450 – Streptococcus himastatinicus
    • 6g5q, 6g5o - P450 – Zobellia galactanivorans
    • 5ysm – AmP450 – Amycolatopsis mediterranei
    • 6f0c, 6f0b - P450 TXTC – Streptomyces acidiscabies
    • 5gwe, 7ccf – CgP450 CreJ – Corynebacterium glutamicum
    • 5y1i - P450 GFSF – Streptomyces graminofaciens
    • 1cpt – PsP450 TERP - Pseudomonas sp.
    • 4l0e, 4l0f - StP450 SKY32– Streptomyces
    • 3awp, 3awq - SpP450-α (mutant) - Sphingomonas paucimobilis
    • 3a4g, 3a4h – PaP450 VDH – Pseudonocardia autotrophica
    • 3a4z, 5gnm, 5gnl - PaP450 VDH (mutant)
    • 3qi8 – P450 – synthetic
    • 6mi0 – McP450 CYP51 – Methylcoccus capsulatus
    • 6ay4, 6ayb, 6ayc – P450 CYP51 + drug – Naegleria fowleri
    • 3dam, 3dan, 3dbm – P45074A2 – Parthenium argentatum
    • 2rcm, 3cli - AtP45074A - Arabidopsis thaliana
    • 6j94 - AtP450 CYP97A3
    • 6l8i - AtP450 CYP97A3 (mutant)
    • 5kyo - P450 CYP101J2 – Sphingobium yanoikuyae
    • 3nv5, 3nv6, 4dxy - NaP450 CYP101D2
    • 6n6q - P450 CYP102L1 – Mycobacterium phage adler
    • 4oqs - AoP450 CYP105AS1
    • 3abb – SaP450 CYP105D6 - Streptomyces avermitilis
    • 3e5j, 3e5l - SaP450 CYP105P1 (mutant)
    • 2z3u - SgP450 CYP105A1 (mutant) – Streptomyces griseolus
    • 5xnt - P450 CYP106A2 – Bacillus butanolivorans
    • 6l39 - SrP450 CYP107G1 – Streptomyces rapamycinicus
    • 4wpz - SaP450 CYP107W1
    • 2whw, 2wi9, 2vz7 – SvP450107L1 (mutant) – Streptomyces venezuelae
    • 2bvj - SvP450107L1
    • 3tkt – NaP450 CYP108D1
    • 5ofq - BmP450 CYP109A2
    • 4rm4 - BsP450 CYP109B1
    • 2jjn, 2jjo - SeP450 CYP113A1 (mutant) - Saccharopolyspora erythraea
    • 6ro8 - P450 CYP116B5 – Acinetobacter radioresistens
    • 1io8, 5bv5 – SsP450 CYP119 (mutant) – Sulfolobus solfataricus
    • 1io9, 1io7, 1f4u - SsP450 CYP119
    • 6cvc – MmP450 CYP124A1 – Mycobacterium marinum
    • 5dqn - MsP450 CYP125A3 (mutant) – Mycobacterium smegmatis
    • 3nc3, 3nc5, 3nc6, 3nc7 - BsP450 CYP134A1 (mutant)
    • 2zqj – BsP450152A1 – Bacillus subtilis
    • 5fyf - MhP450 CYP153A – Marinobacter hydrocarbonoclasticus
    • 6hqg - P450 CYP153 – Phenylobacterium zucineum
    • 6hqd – PsP450 CYP153
    • 7ant – PoP450 CYP153 - Polaromonas
    • 1gwi - ScP450 CYP154C1
    • 6a7i - SvP450 CYP154C4 – Streptomyces violaceruber
    • 2nz5, 2nza, 2dkk – ScP450 CYP158A1 – Streptomyces coelicolor
    • 3r9b – MsP450 CYP164A2
    • 6dcd – MmP450 CYP164A6
    • 3o1a – P450 CYP165D3 – Actinoplanes teichomyceticus
    • 1n97 – TtP450 CYP175A1
    • 4dnz – RpP450 CYP199A4 – Rhodopseudomonas palustris
    • 2z3t - StrP450 CYP245A1 - Streptomyces sp.
    • 5liv - ScP450 CYP260A1
    • 6f85 - ScP450 CYP260A1 (mutant)
    • 5hiw - ScP450 CYP260B1
    • 6gk5 - ScP450 CYP267B1
    • 6g71 - P450 CYP1232A24 - Arthrobacter
    • 6m4q - SspP450 – Streptomyces spectabilis
    • 6j82 - SbP450 TleB – Streptomyces blastmyceticus
    • 6kbh – ReP450 – Rhodococcus erythropolis
  • Other CYPs complexes
    • 2rfc – PtP450+phenylimidazole
    • 3wec – ReP450 + dihydroxy-aurachin Re
    • 5ysw – AmP450+ rifamycin
    • 5omu – AmP450+ syringol
    • 5oms – AmP450+ guaethol
    • 5ncb – AmP450+ guaiacol
    • 5omr – AmP450+ vanilin
    • 6hqk, 6hql. 6hqm, 6hqn, 6hqo, 6hqp – AoP450 (mutant) + guaiacol
    • 6hqs – AoP450 + syringol
    • 6hqq, 6hqr, 6hqt – AoP450 (mutant) + syringol
    • 4pwv, 4pxh - StP450 SKY32 + peptidyl carrier protein domain
    • 2zqx - BsP450 BS b +heptanoic acid
    • 1izo – BsP450 BS beta+ palmitoleic acid
    • 3awm – SpP450-α + palmitic acid
    • 3a50, 3a51 - PaP450 VDH (mutant) + vitamin D3
    • 5xjn – CgP450 CREJ + ethylphenyl derivative
    • 5fsa – P450 CYP51 (mutant) + posaconazole – Candida albicans
    • 6fmo – P450 CYP51 (mutant) + obtosifoliol – Trypanosoma cruzi
    • 6mcw – McP450 CYP51 + detergent
    • 2rch, 3dsi – AtP450 CYP74A+13(S)-HOD
    • 3dsj - AtP450 CYP74A (mutant)+13(S)-HOD
    • 2rcl - AtP450 CYP74A+vernolic acid
    • 3dsk - AtP450 CYP74A (mutant)+ vernolic acid
    • 6a15 - AtP450 CYP90B1 (mutant) + cholesterol
    • 6a16 - AtP450 CYP90B1 (mutant) + uniconazole
    • 6a17 - AtP450 CYP90B1 (mutant) + brassinazole
    • 6a18 - AtP450 CYP90B1 (mutant) + hexanediol
    • 6j94 - AtP450 CYP97A3 + retinal
    • 6l8j - AtP450 CYP97A3 (mutant) + retinal
    • 3cv9, 2zbz - SgP450 CYP105A1 (mutant)+vitamin D3
    • 2zbx - SgP450 CYP105A1+imidazole
    • 5x7e - SgP450 CYP105A1 (mutant)+vitamin D2<br /
    • 3aba – SaP450 CYP105P1+filipin I
    • 3e5k - SaP450 CYP105P1 (mutant)+4-phenylimidazole
    • 4oqr - AoP450 CYP105AS1 (mutant) + compactin
    • 1jin, 1jip - SeP450 CYP107A1+ ketoconazole
    • 1jio, 1oxa - SeP450 CYP107A1+6DEB
    • 1eup – SeP450 CYP107A1+androstendione
    • 1egy - SeP450 CYP107A1+aminophenanthrene
    • 6kzs - SgP450 CYP107F1 + imidazole
    • 6l3a - SrP450 CYP107G1 + drug
    • 4wq0 - SaP450 CYP107W1 + oligomycin
    • 2vzm – SvP450 CYP107L1 (mutant)+narbomycin
    • 2c7x - SvP450 CYP107L1+narbomycin
    • 2cd8, 2ca0, 2c6h – SvP450 CYP107L1+YC-17
    • 2jjp - SeP450 CYP113A1 (mutant)+ketoconazole
    • 2xfh - SeP450 CYP113A1 (mutant)+clotrimazole
    • 1f4t - SsP450 CYP119+ phenylimidazole
    • 4tt5, 4tuv, 4wpd, 4wqj - P450 CYP119+ imidazole derivative – Sulfolobus acidocaldarius
    • 5yhj - P450 CYP152N1 + myristic acid - Exiguobacterium
    • 5fyg - MhP450 CYP153A + dodecanoic acid
    • 7ao7 – PoP450 CYP153 + octanol
    • 6to2 - NfP450 CYP154C4 + androstan derivative – Nocardia farcinica
    • 4j6b, 4jbc, 4jbd, 4jbt - NfP450 CYP154C5 + hormone
    • 6a7j - SvP450 CYP154C4 + testosterone
    • 3r9c – MsP450 CYP164A2 + econazole
    • 4do1, 4egm, 6c3j, 6c3h, 6c2d, 5yqh, 5yqa, 5uvb, 5u6w, 5u6u, 5u6t, 5kt1, 5kdb, 6oow, 6pq6, 6pqd, 6pqs, 6pqw, 6prr, 6prs, 6u30, 6u31, 6u3k – RpP450 CYP199A4 + benzoate derivative
    • 5kdz, 5kdy, 6oox – RpP450 CYP199A4 (mutant) + benzoate derivative
    • 4egn – RpP450 CYP199A4 + veratric acid
    • 4egp – RpP450 CYP199A4 + naphthoic acid
    • 46unn – RpP450 CYP199A4 + cinnamic acid derivative
    • 4ego – RpP450 CYP199A4 + indole derivative
    • 3a1l – StrP450 CYP245A1+dichlorochrompyrrolic acid
    • 6f88, 6f8c - ScP450 CYP260A1 (mutant) + progesterone
    • 6f8a - ScP450 CYP260A1 (mutant) + histidine
    • 6gk6 - ScP450 CYP267B1 + myristic acid
    • 6bld - MmP450 CYP268A2 + pseudoionone
    • 4r20 - zP450 17A2 + abiraterone – zebra fish
    • 6b82 - zP450 17A1 (mutant) + abiraterone
    • 6m4p - SspP450 + antibiotic
    • 6zi3 - P450 + rhamnose – Streptomyces antibioticus
    • 6j84 - SbP450 TleB + hydroxyl analog
    • 6j83 - SbP450 TleB + NMVT

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Openfox

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