Protein phosphatase 3D structures: Difference between revisions

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**[[5zqv]] - hPP1 regulatory subunit 3A + PP1A - human<br />
**[[5zqv]] - hPP1 regulatory subunit 3A + PP1A - human<br />
**[[6dno]] - hPP1 regulatory subunit 3A + PP1A + microcystin-LR<br />
**[[6dno]] - hPP1 regulatory subunit 3A + PP1A + microcystin-LR<br />
**[[5zt0]] - hPP1 regulatory subunit 3B + PP1A<br />
**[[2mb3]] - raPP1 regulatory subunit 3A CBD 102-237 - rabbit<br />
**[[2eef]] - hPP1 regulatory subunit 3B CBM domain 8-156 – NMR<br />
**[[5zt0]] - hPP1 regulatory subunit 3B 31-105 + PP1A<br />
**[[7qf7]], [[7qfa]] - hPP1 regulatory subunit 3C CBM21 domain 132-264 (mutant) + cyclodextrin<br />
**[[7qf7]], [[7qfa]] - hPP1 regulatory subunit 3C CBM21 domain 132-264 (mutant) + cyclodextrin<br />
**[[6hkw]], [[6mky]] - hPP1 regulatory subunit 7<br />
**[[6hkw]], [[6mky]] - hPP1 regulatory subunit 7<br />
**[[6obn]], [[6obp]] - hPP1 regulatory subunit 7 + PP1-A<br />
**[[6obn]], [[6obp]] - hPP1 regulatory subunit 7 + PP1-A<br />
**[[5huz]] - hPP1 regulatory subunit 12A - NMR<br />
**[[6zv2]] – hPP1A regulatory subunit 10 N-terminal - NMR<br />
**[[6zv2]] – hPP1A regulatory subunit 10 N-terminal - NMR<br />
**[[2kjy]], [[5huz]] - hPP1 regulatory subunit 12A - NMR<br />
**[[4xpn]] - hPP1 regulatory subunit 15A + PP1A<br />
**[[7nxv]] – hPP1A regulatory subunit 15A + actin + DNase I<br />
**[[7nxv]] – hPP1A regulatory subunit 15A + actin + DNase I<br />
**[[4xpn]] - hPP1 regulatory subunit 15A + PP1A<br />
**[[9hvf]] – hPP1A regulatory subunit 15B + EIF2 + EIF2B – Cryo EM<br />
**[[2rlt]] - PP1 regulatory subunit 14A - pig - NMR<br />
**[[2rlt]] - PP1 regulatory subunit 14A - pig - NMR<br />
**[[6vti]] - PP1 regulatory subunit 1G N-terminal - rat - NMR<br />
**[[6vti]] - rPP1 regulatory subunit 1G N-terminal - rat - NMR<br />
**[[9ci7]] - rPP1 regulatory subunit 10 (mutant) + Tox4<br />
**[[7lqt]] - rPP1 regulatory subunit 10/Myc homology box - NMR<br />
**[[4v0u]] - mPP1 regulatory subunit 15B + PP1G + actin + ATP - mouse<br />
**[[4v0u]] - mPP1 regulatory subunit 15B + PP1G + actin + ATP - mouse<br />
**[[7nd2]] – hPP1A regulatory subunit 21 in Ferry complex – Cryo EM<br />
**[[8b5r]] – hPP1A regulatory subunit 22 in p97-p37-SPI complex – Cryo EM<br />
**[[8iyj]] – mPP1A regulatory subunit 32 in sperm flagellar microtubule complex – Cryo EM<br />
**[[8otz]] – bPP1A regulatory subunit 32 in sperm flagellar microtubule complex – Cryo EM<br />
*Protein phosphatase 1 regulatory subunit 9A or neurabin-1
**[[1wf8]] - hPP1 regulatory subunit 9A PDZ domain 144-237 - NMR<br />
**[[9gsu]] - hPP1 regulatory subunit 9A 423-593 + PP - NMR<br />
**[[2fn5]] - rPP1 regulatory subunit 9A PDZ domain 502-594 - NMR<br />
**[[2gle]] - rPP1 regulatory subunit 9A SAM domain 986-1056 - NMR<br />
*Protein phosphatase 1 regulatory subunit 9B or neurabin-2 or spinophilin
**[[2g5m]] - rPP1 regulatory subunit 9B PDZ domain 493-602 - NMR<br />
*Protein phosphatase 1A catalytic subunit 1-330
**[[3fxj]], [[3fxk]], [[3fxl]], [[3fxm]], [[3fxo]], [[4mov]] – hPP1A + Mn <br />
**[[6obs]] – hPP1A (mutant) + Mn <br />
**[[6g0j]], [[6g0i]] – hPP1A + Fe <br />
**[[6zk6]] – hPP1A catalytic subunit (mutant) + Mn + Fe<br />
**[[6alz]] – hPP1A catalytic subunit + inhibitor + Mn<br />
**[[3n5u]] – hPP1A + retinoblastoma-associated protein<br />
**[[4g9j]], [[5ioh]], [[8sw5]], [[8sw6]] – hPP1A + peptide<br />
**[[2bdx]], [[6obq]], [[6obr]], [[6obu]] – hPP1A catalytic subunit + microcystin<br />
**[[5ioh]] – hPP1A catalytic subunit + cell division cycle-associated protein<br />
**[[3hvq]] – hPP1A catalytic subunit + neurabin<br />
**[[3egg]] – hPP1A catalytic subunit + spinophilin<br />
**[[3egh]] – hPP1A catalytic subunit + spinophilin + nodularin<br />
**[[1u32]] – hPP1A catalytic subunit + okadaic acid<br />
**[[3e7b]] – hPP1A catalytic subunit + tautomycin<br />
**[[6czo]] – hPP1A catalytic subunit + CASC5 protein<br />
**[[6ghm]] – hPP1A catalytic subunit + ASPP2<br />
**[[6dcx]] – hPP1A catalytic subunit + RelA-associated inhibitor<br />
**[[6zee]], [[6zef]], [[6zeg]], [[6zei]], [[6zej] – hPP1A catalytic subunit + Phactr1<br />
**[[6b67]] – hPP1A (mutant) + cyclic peptide<br />
**[[7t0y]] – hPP1A (mutant) + RRP1 peptide<br />
**[[6alz]] – hPP1A catalytic subunit + inhibitor + Mn <br />
**[[8dwk]], [[8dwl]] – hPP1A catalytic subunit + E3 ubiquitin-protein ligase + Mn <br />
**[[7sd0]], [[7upi]], [[9o65]] - hPP1A catalytic subunit + SHOC-2 + MRAS + Mn – Cryo EM<br />
**[[7tvf]], [[7txh]] - hPP1A catalytic subunit + SHOC-2 + MRAS + Mn<br />
**[[9nb9]] - hPP1A catalytic subunit (mutant) + DP7IL + actin + DNAse I – Cryo EM<br />
*Protein phosphatase 1A catalytic+regulatory subunits
**[[5zqv]] – hPP1A catalytic subunit + regulatory subunit 3A<br />
**[[7qm2]] – hPP1A catalytic subunit (mutant) + regulatory subunit 3C (mutant)<br />
**[[4moy]], [[4mp0]] – hPP1A catalytic subunit + regulatory subunit 10<br />
**[[4xpn]] – hPP1A catalytic subunit + regulatory subunit 15A<br />
**[[6obn]], [[6obp]] – hPP1A catalytic subunit + regulatory subunit 7<br />
**[[6dno]] – hPP1A catalytic subunit + regulatory subunit 3A + microcystin<br />
**[[7qfb]] – hPP1A catalytic subunit + regulatory subunit 3C peptide <br />
**[[7nzm]] – hPP1A catalytic subunit + regulatory subunit 15A + EIF-2A + actin – Cryo EM<br />


*Protein phosphatase 1C catalytic subunit 1-330
*Protein phosphatase 1B or PP! beta


**[[3fxj]], [[3fxk]], [[3fxl]], [[3fxm]], [[3fxo]], [[4mov]], [[4ut3]] – hPP1C + Mn <br />
**[[1s70]] - hPP1B catalytic subunit + MYPT1<br />
**[[6obs]] – hPP1C (mutant) + Mn <br />
**[[6g0j]], [[6g0i]] – hPP1C + Fe <br />
**[[6zk6]] – hPP1C (mutant) + Mn + Fe<br />
**[[6alz]] – hPP1C + inhibitor + Mn<br />
**[[3n5u]] – hPP1C + retinoblastoma-associated protein<br />
**[[4g9j]], [[5ioh]] – hPP1C + peptide<br />
**[[6obq]], [[6obr]], [[6obu]] – hPP1C + microcystin<br />
**[[5ioh]] – hPP1C + cell division cycle-associated protein<br />
**[[6czo]] – hPP1C + CASC5 protein<br />
**[[6ghm]] – hPP1C + ASPP2<br />
**[[6dcx]] – hPP1C + RelA-associated inhibitor<br />
**[[6zee]], [[6zef]] – hPP1C + Phactr1<br />
**[[6b67]] – hPP1C (mutant) + peptide<br />
**[[6alz]] – hPP1C + inhibitor + Mn <br />
**[[8dwk]], [[8dwl]] – hPP1C + E3 ubiquitin-protein ligase + Mn <br />
**[[7sd0]], [[7upi]] - hPP1C + SHOC-2 + MRAS + Mn – Cryo EM<br />
**[[7tvf]], [[7txh]] - hPP1C + SHOC-2 + MRAS + Mn<br />


*Protein phosphatase 1 catalytic+regulatory subunits
*Protein phosphatase 1D


**[[5zqv]] – hPP1C + regulatory subunit 3A<br />
**[[8t2j]] - hPP1D catalytic subunit (mutant)<br />
**[[7qm2]] – hPP1C (mutant) + regulatory subunit 3C (mutant)<br />
**[[4moy]], [[4mp0]] – hPP1C + regulatory subunit 10<br />
**[[4xpn]] – hPP1C + regulatory subunit 15A<br />
**[[6obn]], [[6obp]] – hPP1C + regulatory subunit 7<br />
**[[6dno]] – hPP1C + regulatory subunit 3A + microcystin<br />
**[[7qfb]] – hPP1C + regulatory subunit 3C peptide <br />
**[[7nzm]] – hPP1C + regulatory subunit 15A + EIF-2A + actin – Cryo EM<br />


*Protein phosphatase 1 gamma
*Protein phosphatase 1G or PP! gamma


**[[4ut2]] - hPP1G catalytic subunit<br />
**[[4ut2]], [[4ut3]] - hPP1G catalytic subunit<br />
**[[5inb]], [[5j28]] - hPP1G catalytic subunit + peptide<br />
**[[5inb]], [[5j28]] - hPP1G catalytic subunit + peptide<br />
**[[1it6]] - hPP1G catalytic subunit + inhibitor<br />
**[[2bcd]] - hPP1G catalytic subunit + peptide inhibitor<br />
**[[1jk7]] – hPP1G catalytic subunit + okadaic acid<br />
**[[9ijj]] – mPP1G catalytic subunit in axoneme<br />
**[[4v0v]], [[4v0w]], [[4v0x]] - mPP1G catalytic subunit + hPP1 regulatory subunit 15B peptide<br />
**[[4v0v]], [[4v0w]], [[4v0x]] - mPP1G catalytic subunit + hPP1 regulatory subunit 15B peptide<br />
**[[4v0u]] – mPP1G  catalytic subunit + regulatory subunit 15B + actin + Mn + ATP<br />
**[[4v0u]] – mPP1G  catalytic subunit + regulatory subunit 15B + actin + Mn + ATP<br />
*Protein phosphatase 1H
**[[7kpr]], [[7l4j]], [[7n0z]] - hPP1H <br />
**[[7l4i]] - hPP1H (mutant)<br />


*Protein phosphatase 1K
*Protein phosphatase 1K
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**[[6ak7]] – hPP1K (mutant) + Mg<br />
**[[6ak7]] – hPP1K (mutant) + Mg<br />


*Protein phosphatase 2A or serine/threonine-protein phosphatase 2A
*Protein phosphatase 2A regulatory subunits or serine/threonine-protein phosphatase 2A regulatory subunits
 
**[[4i5j]], [[4i5k]], [[4mew]] – hPP2A b” regulatory subunit <br />
**[[2g62]], [[2ixm]] – hPP2A b’ regulatory subunit <br />
**[[2hv6]] – hPP2A b regulatory subunit <br />
**[[2hv7]] – hPP2A b regulatory subunit + ADP<br />
**[[2jak]] – hPP2A 56 regulatory subunit <br />
**[[1b3u]] – hPP2A 65 regulatory subunit <br />
**[[5jja]], [[5k6s]], [[5swf]] – hPP2A 56 regulatory subunit + BUBR1<br />
**[[5sw9]] – hPP2A 56 regulatory subunit + RepoMan<br />
**[[6toq]] – hPP2A 56 regulatory subunit + pol protein<br />
**[[6voy]] – hPP2A 56 regulatory subunit + DNA-binding protein DNA - Cryo EM<br />
**[[6oyl]] – hPP2A 56 regulatory subunit + KIF4A<br />
**[[6vro]] – hPP2A 56 regulatory subunit + AIM1<br />
**[[9gnj]] – hPP2A 56 regulatory subunit + BRCA2<br />
**[[7ouf]], [[7oug]], [[7ouh]], [[7pel]] – hPP2A 56 regulatory subunit in virus intasome + drug – Cryo EM<br />
**[[8szk]] – hPP2A 56 regulatory subunit + elongin B,C + CBFB – Cryo EM<br />
**[[2pf4]], [[2pkg]] – hPP2A 65 regulatory subunit + small T antigen<br />
**[[6ef4]] – mPP2A regulatory subunit (mutant) - mouse<br />
**[[5w0w]] – mPP2A + TIPRL<br />
**[[7xvk]] – AtPP2A 65 regulatory subunit + PSR2 - ''Arabidopsis thaliana'' <br />
 
*Protein phosphatase 2A catalytic subunit
 
**[[4lac]] – hPP2A catalytic subunit + activator + PP2A scaffold subunit<br />
**[[9o04]] – hPP2A catalytic subunit in degradosome complex – Cryo EM<br />
**[[9o0l]] – hPP2A catalytic subunit + CCDC6 – Cryo EM<br />
**[[3p71]]  – hPP2A catalytic + LCMT-1 <br />
**[[4iyp]] – hPP2A catalytic subunit + immunoglobin-binding protein<br />
 
*Protein phosphatase 2A regulatory subunits + catalytic subunit


**[[1b3u]], [[2g62]], [[2hv6]], [[4mew]], [[4i5k]], [[4i5j]], [[2jak]], [[2ixm]], [[2hv7]] – hPP2A regulatory subunit <br />
**[[7k36]] – hPP2A 65 regulatory subunit + catalytic subunit in STRIPAK complex – Cryo EM<br />
**[[5swf]], [[5k6s]], [[5jja]] – hPP2A regulatory subunit + BUBR1<br />
**[[7ycx]] – hPP2A 65 regulatory subunit + catalytic subunit in integrator-PEC complex – Cryo EM<br />
**[[5sw9]] – hPP2A regulatory subunit + RepoMan<br />
**[[9vd9]] – hPP2A 65 regulatory subunit + catalytic subunit in dss1-integrator-PEC complex – Cryo EM<br />
**[[6toq]] – hPP2A regulatory subunit + pol protein<br />
**[[8rbx]] – hPP2A 65 regulatory subunit + catalytic subunit in RNA polymerase-nucleosome  complex – Cryo EM<br />
**[[6voy]] – hPP2A regulatory subunit + DNA-binding protein DNA - Cryo EM<br />
**[[8rbz]] – hPP2A 65 regulatory subunit + catalytic subunit in integrator-SOSS complex – Cryo EM<br />
**[[6oyl]] – hPP2A regulatory subunit + KIF4A<br />
**[[8rc4]], [[8yjb]] – hPP2A 65 regulatory subunit + catalytic subunit in integrator-DSS1 complex – Cryo EM<br />
**[[6vro]] – hPP2A regulatory subunit + AIM1<br />
**[[7soy]] – hPP2A catalytic  subunit + regulatory subunits 56,65 + PME-1 – Cryo EM<br />
**[[7ouf]], [[7oug]], [[7pel]] – hPP2A regulatory subunit in virus intasome – Cryo EM<br />
**[[8uwb]], [[9mf5]], [[9mip]], [[9mzw]] – hPP2A catalytic  subunit + regulatory subunits 56,65 – Cryo EM<br />
**[[2pkg]], [[2pf4]] – hPP2A regulatory subunit + small T antigen<br />
**[[8u1x]], [[8u89]] – hPP2A catalytic  subunit + regulatory subunits 56 (mutant),65 – Cryo EM<br />
**[[7soy]] – hPP2A catalytic  subunit + PME-1 + b56gamma1 – Cryo EM<br />
**[[2ie3]], [[2ie4]], [[2npp]], [[2nyl]], [[2nym]] – hPP2A catalytic + regulatory 56 subunit + tumor-inducing toxin<br />
**[[2ie3]], [[2ie4]], [[2npp]], [[2nyl]], [[2nym]] – hPP2A catalytic + regulatory subunit + tumor-inducing toxin<br />
**[[3c5w]] – hPP2A catalytic + regulatory subunit + PP2A-specific methyltransferase<br />
**[[3c5w]] – hPP2A catalytic + regulatory subunit + PP2A-specific methyltransferase<br />
**[[6nts]] – hPP2A catalytic + regulatory subunit + activator – Cryo EM<br />
**[[6nts]] – hPP2A catalytic + regulatory subunits 56,65 + activator – Cryo EM<br />
**[[3p71]], [[2iae]] – hPP2A catalytic + regulatory subunit + LCMT-1 <br />
**[[9c7t]], [[9n0y]] – hPP2A catalytic + regulatory subunits 56,65 + EYA3 – Cryo EM<br />
**[[3dw8]] – hPP2A catalytic + regulatory subunit (mutant) + LCMT-1 <br />
**[[9c6b]] – hPP2A catalytic + regulatory subunits 56,65 + retinoblastoma-like protein – Cryo-EM<br />
**[[3fga]] – hPP2A catalytic + regulatory subunit + LCMT-1 + SGO<br />
**[[8so0]], [[8twe]], [[8twi]] – hPP2A catalytic + regulatory subunits 56,65 + Fam122A – Cryo EM<br />
**[[4i5n]], [[4i5l]] – hPP2A catalytic + regulatory subunit + MCLR<br />
**[[8ttb]] – hPP2A catalytic + regulatory subunits 56,65 + CAMP-regulated phosphoprotein – Cryo EM<br />
**[[3k7w]] – hPP2A catalytic + regulatory subunit + toxin<br />
**[[9n0z]] – hPP2A catalytic + regulatory subunits 56,65 + B55I inhibitor – Cryo EM<br />
**[[7cun]], [[7pks]] – hPP2A catalytic + regulatory subunit + integrator complex – Cryo EM<br />
**[[2iae]], [[3dws]]  – hPP2A catalytic + regulatory subunits 56,65 + microcystin-LR <br />
**[[4iyp]] – hPP2A catalytic subunit + immunoglobin-binding protein<br />
**[[3fga]] – hPP2A catalytic + regulatory subunits 56,65 + microcystin-LR + shugoshin<br />
**[[6ef4]] – mPP2A reglatory subunit (mutant) - mouse<br />
**[[4i5l]], [[4i5n]] – hPP2A catalytic + regulatory subunits 65,b” + MCLR<br />
**[[5w0w]] – mPP2A + TIPRL<br />
**[[3k7w]] – hPP2A catalytic + regulatory subunit 65 + toxin<br />
**[[7cun]], [[7pks]] – hPP2A catalytic + regulatory subunit 65 + integrator complex – Cryo EM<br />
**[[8uo5]] – hPP2A catalytic + regulatory subunit 55 + IER5 – Cryo EM<br />
**[[5w0w]] – mPP2A 65 regulatory subunit + catalytic subunit + TIPRL<br />
**[[9j5n]], [[9j5r]] – AtPP2A 65 regulatory subunit + catalytic subunit + PSR2 <br />


*Protein phosphatase 2B See [[Calcineurin]]
*Protein phosphatase 2B See [[Calcineurin]]


*Protein phosphatase 2C
*Protein phosphatase 2C or pyruvate dehydrogenase phosphatase


**[[2iq1]] – hPP2C κ <br />
**[[4ra2]], [[4raf]], [[4rag]] - hPP2C α (mutant) + Mn<br />
**[[4ra2]], [[4raf]], [[4rag]] - hPP2C α (mutant) + Mn<br />
**[[2iq1]] – hPP2C κ <br /
**[[3mq3]], [[6v0t]] - bPP2C catalytic subunit + Mn<br />
**[[2pnq]] - rPP2C catalytic subunit <br />
**[[3d8k]] – PP2C – ''Toxoplasma gondii''<br />
**[[3d8k]] – PP2C – ''Toxoplasma gondii''<br />
**[[3ujk]] – AtPP2C - ''Arabidopsis thaliana'' <br />
**[[4la7]], [[4lg5]], [[4lga]], [[4lgb]] – AtPP2C 16 + abscisic acid receptor Pyl2 + ligand <br />
**[[4yzg]] – AtPP2C (mutant) <br />
**[[5vr7]], [[5vro]], [[5vs5]], [[5vsq]], [[5vsr]], [[5vt7]] – AtPP2C 16 + abscisic acid receptor Pyl2 + quinolone derivative<br />
**[[3jrq]], [[3nmn]] – AtPP2C + abscisic acid receptor Pyl1 + pyrabactin <br />
**[[4ds8]], [[5jo1]], [[5jo2]] – AtPP2C 16 + abscisic acid receptor Pyl3 + Mn<br />
**[[3kdj]], [[7avn]] - AtPP2C + abscisic acid receptor Pyl1 + abscicic acid<br />
**[[3rt0]] – AtPP2C 16 (mutant) + abscisic acid receptor Pyl10<br />
**[[3nmt]], [[3kb3]], [[3nmv]], [[3ujl]] – AtPP2C + abscisic acid receptor Pyl2<br />
**[[3ujg]] - AtPP2C 16 + SRK2E<br />
**[[4la7]], [[4lg5]], [[4lga]], [[4lgb]] – AtPP2C + abscisic acid receptor Pyl2 + ligand<br />
**[[5mn0]] – AtPP2C 16 + ABA receptor <br />
**[[5vr7]], [[5vro]], [[5vs5]], [[5vsq]], [[5vsr]], [[5vt7]] – AtPP2C + abscisic acid receptor Pyl2 + quinolone derivative<br />
**[[6zuc]], [[7avw]] – AtPP2C 16 + CSPYL1 + agonist<br />
**[[4ds8]], [[5jo1]], [[5jo2]] – AtPP2C + abscisic acid receptor Pyl3 + Mn<br />
**[[3qn1]], [[3zvu]], [[4wvo]] – AtPP2C 16 + abscisic acid receptor Pyr1<br />
**[[3rt0]] – AtPP2C (mutant) + abscisic acid receptor Pyl10<br />
**[[5or2]], [[5or6]], [[8ay3]], [[8ay6]], [[8ay7]], [[8ay8]], [[8ay9]], [[8aya]], [[9tb5]], [[9tb6]], [[9tb7]], [[9tb8]], [[9tb9]], [[9tbb]], [[9tbc]] – AtPP2C 16 + abscisic acid receptor Pyr1 + abscisic acid analog<br />
**[[4n0g]] – AtPP2C + abscisic acid receptor Pyl13<br />
**[[8ey0]] – AtPP2C 16 + abscisic acid receptor Pyr1 + fungicide<br />
**[[3qn1]], [[3zvu]], [[4wvo]] – AtPP2C + abscisic acid receptor Pyr1<br />
**[[9h0h]], [[9h0i]], [[9h0j]] – AtPP2C 16 + abscisic acid receptor Pyr1 + agonist<br />
**[[5or2]], [[5or6]], [[8ay3]], [[8ay6]], [[8ay7]], [[8ay8]], [[8ay9]], [[8aya]] – AtPP2C + abscisic acid receptor Pyr1 + abscicic acid analog<br />
**[[4n0g]] – AtPP2C 37 + abscisic acid receptor Pyl13<br />
**[[4yzh]] – AtPP2C (mutant) + chlorophyll-binding protein peptide<br />
**[[3jrq]], [[3nmn]] – AtPP2C 56 + abscisic acid receptor Pyl1 + pyrabactin <br />
**[[3ujg]] - AtPP2C + SRK2E<br />
**[[3kdj]] - AtPP2C 56 + abscisic acid receptor Pyl1 + abscicic acid<br />
**[[5mn0]] – AtPP2C + ABA receptor <br />
**[[4yzg]] – AtPP2C 57 (mutant) <br />
**[[4yzh]] – AtPP2C 57 (mutant) + chlorophyll-binding protein peptide<br />
**[[3ujk]] AtPP2C 77 <br />
**[[3kb3]], [[3nmt]], [[3nmv]], [[3ujl]] – AtPP2C 77 + abscisic acid receptor Pyl2<br />
**[[5zch]] – PP2C + abscisic acid receptor Pyl3 - rice<br />
**[[5zch]] – PP2C + abscisic acid receptor Pyl3 - rice<br />


Line 116: Line 201:


**[[6r8i]] – PP4 regulatory subunit + peptide<br />
**[[6r8i]] – PP4 regulatory subunit + peptide<br />
**[[4wsf]] – PP4 regulatory subunit + Cenp-C – ''Drosophila melanogaster''<br />
**[[4wsf]] – DmPP4 regulatory subunit + Cenp-C – ''Drosophila melanogaster''<br />


*Protein phosphatase 5 or Protein phosphatase T
*Protein phosphatase 5 or Protein phosphatase T
Line 122: Line 207:
**[[1wao]] – hPP5 + Mn<br />
**[[1wao]] – hPP5 + Mn<br />
**[[5muf]] – hPP5 <br />
**[[5muf]] – hPP5 <br />
**[[7zr5]] – hPP5 + Hsp90 + CDC37 – Cryo EM<br />
**[[7zr6]] – hPP5 + Hsp90 + CDC37 + Braf – Cryo EM<br />
**[[8gae]], [[8gft]] – hPP5 + Hsp90 + CDC37 + Craf – Cryo EM<br />
**[[1a17]] – hPP5 protein-interacting domain<br />
**[[1a17]] – hPP5 protein-interacting domain<br />
**[[2bug]] – hPP5 protein-interacting domain (mutant) + Hsp90 peptide - NMR<br />
**[[2bug]] – hPP5 protein-interacting domain (mutant) + Hsp90 peptide - NMR<br />
Line 138: Line 220:
*Protein phosphatase
*Protein phosphatase


**[[8jfw]], [[8jfy]] – DmPP rdgC + calmodulin – Cryo EM<br />
**[[8zlw]] – DmPP rdgC + MBP + calmodulin – Cryo EM<br />
**[[9tp5]] – AtPP BSU1 kelch domain 1-357 <br />
**[[9tp7]] – AtPP BSU1 421-793<br />
**[[9tp8]] – AtPP BSU1 421-793 (mutant)<br />
**[[8pq7]] – PP + RXLR effector protein – potato<br />
**[[1g5b]] – PP + Mn – Enterobacteria phage λ<br />
**[[1g5b]] – PP + Mn – Enterobacteria phage λ<br />
**[[2pk0]] – PP + Mg – ''Streptococcus agalactiae''<br />
**[[2pk0]] – PP + Mg – ''Streptococcus agalactiae''<br />
Line 145: Line 233:
**[[5jpe]] – CaPP Z1 + Mn – ''Candida albicans''<br />
**[[5jpe]] – CaPP Z1 + Mn – ''Candida albicans''<br />
**[[5jpf]] – CaPP Z1 + microcystin-LR + Mn <br />
**[[5jpf]] – CaPP Z1 + microcystin-LR + Mn <br />
}}
}}


[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 07:14, 9 August 2026

3D Structures of protein phosphatase

Updated on 09-August-2026 {{#tree:id=OrganizedByTopic|openlevels=0|

  • Protein phosphatase 1 regulatory subunit
    • 5zqv - hPP1 regulatory subunit 3A + PP1A - human
    • 6dno - hPP1 regulatory subunit 3A + PP1A + microcystin-LR
    • 2mb3 - raPP1 regulatory subunit 3A CBD 102-237 - rabbit
    • 2eef - hPP1 regulatory subunit 3B CBM domain 8-156 – NMR
    • 5zt0 - hPP1 regulatory subunit 3B 31-105 + PP1A
    • 7qf7, 7qfa - hPP1 regulatory subunit 3C CBM21 domain 132-264 (mutant) + cyclodextrin
    • 6hkw, 6mky - hPP1 regulatory subunit 7
    • 6obn, 6obp - hPP1 regulatory subunit 7 + PP1-A
    • 6zv2 – hPP1A regulatory subunit 10 N-terminal - NMR
    • 2kjy, 5huz - hPP1 regulatory subunit 12A - NMR
    • 4xpn - hPP1 regulatory subunit 15A + PP1A
    • 7nxv – hPP1A regulatory subunit 15A + actin + DNase I
    • 9hvf – hPP1A regulatory subunit 15B + EIF2 + EIF2B – Cryo EM
    • 2rlt - PP1 regulatory subunit 14A - pig - NMR
    • 6vti - rPP1 regulatory subunit 1G N-terminal - rat - NMR
    • 9ci7 - rPP1 regulatory subunit 10 (mutant) + Tox4
    • 7lqt - rPP1 regulatory subunit 10/Myc homology box - NMR
    • 4v0u - mPP1 regulatory subunit 15B + PP1G + actin + ATP - mouse
    • 7nd2 – hPP1A regulatory subunit 21 in Ferry complex – Cryo EM
    • 8b5r – hPP1A regulatory subunit 22 in p97-p37-SPI complex – Cryo EM
    • 8iyj – mPP1A regulatory subunit 32 in sperm flagellar microtubule complex – Cryo EM
    • 8otz – bPP1A regulatory subunit 32 in sperm flagellar microtubule complex – Cryo EM
  • Protein phosphatase 1 regulatory subunit 9A or neurabin-1
    • 1wf8 - hPP1 regulatory subunit 9A PDZ domain 144-237 - NMR
    • 9gsu - hPP1 regulatory subunit 9A 423-593 + PP - NMR
    • 2fn5 - rPP1 regulatory subunit 9A PDZ domain 502-594 - NMR
    • 2gle - rPP1 regulatory subunit 9A SAM domain 986-1056 - NMR
  • Protein phosphatase 1 regulatory subunit 9B or neurabin-2 or spinophilin
    • 2g5m - rPP1 regulatory subunit 9B PDZ domain 493-602 - NMR
  • Protein phosphatase 1A catalytic subunit 1-330


    • 2bdx, 6obq, 6obr, 6obu – hPP1A catalytic subunit + microcystin
    • 5ioh – hPP1A catalytic subunit + cell division cycle-associated protein
    • 3hvq – hPP1A catalytic subunit + neurabin
    • 3egg – hPP1A catalytic subunit + spinophilin
    • 3egh – hPP1A catalytic subunit + spinophilin + nodularin
    • 1u32 – hPP1A catalytic subunit + okadaic acid
    • 3e7b – hPP1A catalytic subunit + tautomycin
    • 6czo – hPP1A catalytic subunit + CASC5 protein
    • 6ghm – hPP1A catalytic subunit + ASPP2
    • 6dcx – hPP1A catalytic subunit + RelA-associated inhibitor
    • 6zee, 6zef, 6zeg, 6zei, [[6zej] – hPP1A catalytic subunit + Phactr1
    • 6b67 – hPP1A (mutant) + cyclic peptide
    • 7t0y – hPP1A (mutant) + RRP1 peptide
    • 6alz – hPP1A catalytic subunit + inhibitor + Mn
    • 8dwk, 8dwl – hPP1A catalytic subunit + E3 ubiquitin-protein ligase + Mn
    • 7sd0, 7upi, 9o65 - hPP1A catalytic subunit + SHOC-2 + MRAS + Mn – Cryo EM
    • 7tvf, 7txh - hPP1A catalytic subunit + SHOC-2 + MRAS + Mn
    • 9nb9 - hPP1A catalytic subunit (mutant) + DP7IL + actin + DNAse I – Cryo EM
  • Protein phosphatase 1A catalytic+regulatory subunits
    • 5zqv – hPP1A catalytic subunit + regulatory subunit 3A
    • 7qm2 – hPP1A catalytic subunit (mutant) + regulatory subunit 3C (mutant)
    • 4moy, 4mp0 – hPP1A catalytic subunit + regulatory subunit 10
    • 4xpn – hPP1A catalytic subunit + regulatory subunit 15A
    • 6obn, 6obp – hPP1A catalytic subunit + regulatory subunit 7
    • 6dno – hPP1A catalytic subunit + regulatory subunit 3A + microcystin
    • 7qfb – hPP1A catalytic subunit + regulatory subunit 3C peptide
    • 7nzm – hPP1A catalytic subunit + regulatory subunit 15A + EIF-2A + actin – Cryo EM
  • Protein phosphatase 1B or PP! beta
    • 1s70 - hPP1B catalytic subunit + MYPT1
  • Protein phosphatase 1D
    • 8t2j - hPP1D catalytic subunit (mutant)
  • Protein phosphatase 1G or PP! gamma
    • 4ut2, 4ut3 - hPP1G catalytic subunit
    • 5inb, 5j28 - hPP1G catalytic subunit + peptide
    • 1it6 - hPP1G catalytic subunit + inhibitor
    • 2bcd - hPP1G catalytic subunit + peptide inhibitor
    • 1jk7 – hPP1G catalytic subunit + okadaic acid
    • 9ijj – mPP1G catalytic subunit in axoneme
    • 4v0v, 4v0w, 4v0x - mPP1G catalytic subunit + hPP1 regulatory subunit 15B peptide
    • 4v0u – mPP1G catalytic subunit + regulatory subunit 15B + actin + Mn + ATP
  • Protein phosphatase 1H
  • Protein phosphatase 1K
    • 4da1 - hPP1K + Mn
    • 6ak7 – hPP1K (mutant) + Mg
  • Protein phosphatase 2A regulatory subunits or serine/threonine-protein phosphatase 2A regulatory subunits
    • 4i5j, 4i5k, 4mew – hPP2A b” regulatory subunit
    • 2g62, 2ixm – hPP2A b’ regulatory subunit
    • 2hv6 – hPP2A b regulatory subunit
    • 2hv7 – hPP2A b regulatory subunit + ADP
    • 2jak – hPP2A 56 regulatory subunit
    • 1b3u – hPP2A 65 regulatory subunit
    • 5jja, 5k6s, 5swf – hPP2A 56 regulatory subunit + BUBR1
    • 5sw9 – hPP2A 56 regulatory subunit + RepoMan
    • 6toq – hPP2A 56 regulatory subunit + pol protein
    • 6voy – hPP2A 56 regulatory subunit + DNA-binding protein DNA - Cryo EM
    • 6oyl – hPP2A 56 regulatory subunit + KIF4A
    • 6vro – hPP2A 56 regulatory subunit + AIM1
    • 9gnj – hPP2A 56 regulatory subunit + BRCA2
    • 7ouf, 7oug, 7ouh, 7pel – hPP2A 56 regulatory subunit in virus intasome + drug – Cryo EM
    • 8szk – hPP2A 56 regulatory subunit + elongin B,C + CBFB – Cryo EM
    • 2pf4, 2pkg – hPP2A 65 regulatory subunit + small T antigen
    • 6ef4 – mPP2A regulatory subunit (mutant) - mouse
    • 5w0w – mPP2A + TIPRL
    • 7xvk – AtPP2A 65 regulatory subunit + PSR2 - Arabidopsis thaliana
  • Protein phosphatase 2A catalytic subunit
    • 4lac – hPP2A catalytic subunit + activator + PP2A scaffold subunit
    • 9o04 – hPP2A catalytic subunit in degradosome complex – Cryo EM
    • 9o0l – hPP2A catalytic subunit + CCDC6 – Cryo EM
    • 3p71 – hPP2A catalytic + LCMT-1
    • 4iyp – hPP2A catalytic subunit + immunoglobin-binding protein
  • Protein phosphatase 2A regulatory subunits + catalytic subunit
    • 7k36 – hPP2A 65 regulatory subunit + catalytic subunit in STRIPAK complex – Cryo EM
    • 7ycx – hPP2A 65 regulatory subunit + catalytic subunit in integrator-PEC complex – Cryo EM
    • 9vd9 – hPP2A 65 regulatory subunit + catalytic subunit in dss1-integrator-PEC complex – Cryo EM
    • 8rbx – hPP2A 65 regulatory subunit + catalytic subunit in RNA polymerase-nucleosome complex – Cryo EM
    • 8rbz – hPP2A 65 regulatory subunit + catalytic subunit in integrator-SOSS complex – Cryo EM
    • 8rc4, 8yjb – hPP2A 65 regulatory subunit + catalytic subunit in integrator-DSS1 complex – Cryo EM
    • 7soy – hPP2A catalytic subunit + regulatory subunits 56,65 + PME-1 – Cryo EM
    • 8uwb, 9mf5, 9mip, 9mzw – hPP2A catalytic subunit + regulatory subunits 56,65 – Cryo EM
    • 8u1x, 8u89 – hPP2A catalytic subunit + regulatory subunits 56 (mutant),65 – Cryo EM
    • 2ie3, 2ie4, 2npp, 2nyl, 2nym – hPP2A catalytic + regulatory 56 subunit + tumor-inducing toxin
    • 3c5w – hPP2A catalytic + regulatory subunit + PP2A-specific methyltransferase
    • 6nts – hPP2A catalytic + regulatory subunits 56,65 + activator – Cryo EM
    • 9c7t, 9n0y – hPP2A catalytic + regulatory subunits 56,65 + EYA3 – Cryo EM
    • 9c6b – hPP2A catalytic + regulatory subunits 56,65 + retinoblastoma-like protein – Cryo-EM
    • 8so0, 8twe, 8twi – hPP2A catalytic + regulatory subunits 56,65 + Fam122A – Cryo EM
    • 8ttb – hPP2A catalytic + regulatory subunits 56,65 + CAMP-regulated phosphoprotein – Cryo EM
    • 9n0z – hPP2A catalytic + regulatory subunits 56,65 + B55I inhibitor – Cryo EM
    • 2iae, 3dws – hPP2A catalytic + regulatory subunits 56,65 + microcystin-LR
    • 3fga – hPP2A catalytic + regulatory subunits 56,65 + microcystin-LR + shugoshin
    • 4i5l, 4i5n – hPP2A catalytic + regulatory subunits 65,b” + MCLR
    • 3k7w – hPP2A catalytic + regulatory subunit 65 + toxin
    • 7cun, 7pks – hPP2A catalytic + regulatory subunit 65 + integrator complex – Cryo EM
    • 8uo5 – hPP2A catalytic + regulatory subunit 55 + IER5 – Cryo EM
    • 5w0w – mPP2A 65 regulatory subunit + catalytic subunit + TIPRL
    • 9j5n, 9j5r – AtPP2A 65 regulatory subunit + catalytic subunit + PSR2
  • Protein phosphatase 2C or pyruvate dehydrogenase phosphatase
    • 4ra2, 4raf, 4rag - hPP2C α (mutant) + Mn
    • 2iq1 – hPP2C κ <br /
    • 3mq3, 6v0t - bPP2C catalytic subunit + Mn
    • 2pnq - rPP2C catalytic subunit
    • 3d8k – PP2C – Toxoplasma gondii
    • 4la7, 4lg5, 4lga, 4lgb – AtPP2C 16 + abscisic acid receptor Pyl2 + ligand
    • 5vr7, 5vro, 5vs5, 5vsq, 5vsr, 5vt7 – AtPP2C 16 + abscisic acid receptor Pyl2 + quinolone derivative
    • 4ds8, 5jo1, 5jo2 – AtPP2C 16 + abscisic acid receptor Pyl3 + Mn
    • 3rt0 – AtPP2C 16 (mutant) + abscisic acid receptor Pyl10
    • 3ujg - AtPP2C 16 + SRK2E
    • 5mn0 – AtPP2C 16 + ABA receptor
    • 6zuc, 7avw – AtPP2C 16 + CSPYL1 + agonist
    • 3qn1, 3zvu, 4wvo – AtPP2C 16 + abscisic acid receptor Pyr1
    • 5or2, 5or6, 8ay3, 8ay6, 8ay7, 8ay8, 8ay9, 8aya, 9tb5, 9tb6, 9tb7, 9tb8, 9tb9, 9tbb, 9tbc – AtPP2C 16 + abscisic acid receptor Pyr1 + abscisic acid analog
    • 8ey0 – AtPP2C 16 + abscisic acid receptor Pyr1 + fungicide
    • 9h0h, 9h0i, 9h0j – AtPP2C 16 + abscisic acid receptor Pyr1 + agonist
    • 4n0g – AtPP2C 37 + abscisic acid receptor Pyl13
    • 3jrq, 3nmn – AtPP2C 56 + abscisic acid receptor Pyl1 + pyrabactin
    • 3kdj - AtPP2C 56 + abscisic acid receptor Pyl1 + abscicic acid
    • 4yzg – AtPP2C 57 (mutant)
    • 4yzh – AtPP2C 57 (mutant) + chlorophyll-binding protein peptide
    • 3ujk – AtPP2C 77
    • 3kb3, 3nmt, 3nmv, 3ujl – AtPP2C 77 + abscisic acid receptor Pyl2
    • 5zch – PP2C + abscisic acid receptor Pyl3 - rice
  • Protein phosphatase 4
    • 6r8i – PP4 regulatory subunit + peptide
    • 4wsf – DmPP4 regulatory subunit + Cenp-C – Drosophila melanogaster
  • Protein phosphatase 5 or Protein phosphatase T
    • 1wao – hPP5 + Mn
    • 5muf – hPP5
    • 1a17 – hPP5 protein-interacting domain
    • 2bug – hPP5 protein-interacting domain (mutant) + Hsp90 peptide - NMR
    • 1s95, 3h60 – hPP5 catalytic domain + Mn
    • 3h61, 3h62, 3h63, 3h64, 3h66, 3h67, 3h68, 3h69, 4zvz, 4zx2, 4zvz, 4zx2, 5ui1 – hPP5 catalytic domain + inhibitor + Mn
    • 5wg8 – hPP5 catalytic domain + cancer drug + Mn
    • 5hpe – hPP5 catalytic domain/Hsp90 peptide + Mn
    • 4ja7, 4ja9 - rPP5 catalytic domain + inhibitor
    • 3icf - yPP5 catalytic domain + Fe - yeast
    • 5jjt – AtPP5 + Ni
    • 7obe – AtPP5 + Mn
  • Protein phosphatase
    • 8jfw, 8jfy – DmPP rdgC + calmodulin – Cryo EM
    • 8zlw – DmPP rdgC + MBP + calmodulin – Cryo EM
    • 9tp5 – AtPP BSU1 kelch domain 1-357
    • 9tp7 – AtPP BSU1 421-793
    • 9tp8 – AtPP BSU1 421-793 (mutant)
    • 8pq7 – PP + RXLR effector protein – potato
    • 1g5b – PP + Mn – Enterobacteria phage λ
    • 2pk0 – PP + Mg – Streptococcus agalactiae
    • 2cm1 – PP + Mn – Mycobacterium tuberculosis
    • 3pu9 – PP + Mg – Sphaerobacter thermophilus
    • 5f1m – PP Stp1 + Mn – Staphylococcus aureus
    • 5jpe – CaPP Z1 + Mn – Candida albicans
    • 5jpf – CaPP Z1 + microcystin-LR + Mn

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Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Joel L. Sussman