1jr8

Structural highlights

Function

ERV2_YEAST FAD-dependent sulfhydryl oxidase that catalyzes disulfide bond formation in the endoplasmic reticulum lumen in parallel to ERO1.^{[1] [2]}

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

• Sulfhydryl oxidase 3D structures

References

1. ↑ Gerber J, Muhlenhoff U, Hofhaus G, Lill R, Lisowsky T. Yeast ERV2p is the first microsomal FAD-linked sulfhydryl oxidase of the Erv1p/Alrp protein family. J Biol Chem. 2001 Jun 29;276(26):23486-91. Epub 2001 Apr 19. PMID:11313344 doi:http://dx.doi.org/10.1074/jbc.M100134200
2. ↑ Sevier CS, Cuozzo JW, Vala A, Aslund F, Kaiser CA. A flavoprotein oxidase defines a new endoplasmic reticulum pathway for biosynthetic disulphide bond formation. Nat Cell Biol. 2001 Oct;3(10):874-82. PMID:11584268 doi:http://dx.doi.org/10.1038/ncb1001-874