Structural highlights
Function
EST1_RABIT Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs.[1]
Evolutionary Conservation
Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.
See Also
References
- ↑ Potter PM, Pawlik CA, Morton CL, Naeve CW, Danks MK. Isolation and partial characterization of a cDNA encoding a rabbit liver carboxylesterase that activates the prodrug irinotecan (CPT-11). Cancer Res. 1998 Jun 15;58(12):2646-51 PMID:9635592