1kol

Structural highlights

Function

FADH_PSEPU Catalyzes the NAD(+)-dependent oxidation of formaldehyde and acetoaldehyde as well as long-chain alcohols but is inactive against propionaldehyde, butyraldehyde, methanol and ethanol. Can also catalyze the dismutation of a wide range of aldehydes such as formaldehyde.^{[1] [2]}

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

1. ↑ Ogushi S, Ando M, Tsuru D. Formaldehyde dehydrogenase from Pseudomonas putida: a zinc metalloenzyme. J Biochem. 1984 Nov;96(5):1587-91. PMID:6526822
2. ↑ Oppenheimer NJ, Henehan GT, Huete-Perez JA, Ito K. P. putida formaldehyde dehydrogenase. An alcohol dehydrogenase masquerading as an aldehyde dehydrogenase. Adv Exp Med Biol. 1997;414:417-23. PMID:9059646