Crystal structure of the catalytic domain of bovine beta1,4-galactosyltransferase complex with UDP-galactose
Structural highlights
1o0r is a 2 chain structure with sequence from Bos taurus. This structure supersedes the now removed PDB entry 1kyb. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
B4GT1_BOVIN The Golgi complex form catalyzes the production of lactose in the lactating mammary gland and could also be responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids. The cell surface form functions as a recognition molecule during a variety of cell to cell and cell to matrix interactions, as those occurring during development and egg fertilization, by binding to specific oligosaccharide ligands on opposing cells or in the extracellular matrix.
Evolutionary Conservation
Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.
