1pn9

From Proteopedia

Crystal structure of an insect delta-class glutathione S-transferase from a DDT-resistant strain of the malaria vector Anopheles gambiae

Structural highlights

1pn9 is a 2 chain structure with sequence from Anopheles gambiae. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 2Å
Ligands:	GTX
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

GST1D_ANOGA Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Has DDT dehydrochlorinase activity.^[1] ^[2]

Evolutionary Conservation

Checkto colour the structure by Evolutionary Conservation, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

↑ Ranson H, Cornel AJ, Fournier D, Vaughan A, Collins FH, Hemingway J. Cloning and localization of a glutathione S-transferase class I gene from Anopheles gambiae. J Biol Chem. 1997 Feb 28;272(9):5464-8. PMID:9038148
↑ Ranson H, Prapanthadara La, Hemingway J. Cloning and characterization of two glutathione S-transferases from a DDT-resistant strain of Anopheles gambiae. Biochem J. 1997 May 15;324 ( Pt 1):97-102. PMID:9164846

1 Structural highlights
2 Function
3 Evolutionary Conservation
4 See Also
5 References

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PDB ID 1pn9

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1pn9

From Proteopedia

Crystal structure of an insect delta-class glutathione S-transferase from a DDT-resistant strain of the malaria vector Anopheles gambiae

Structural highlights

Function

Evolutionary Conservation

See Also

References

Contents

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