1r8d

Structural highlights

Function

MTA_BACSU Global transcriptional regulator that activates transcription of bmr and blt by binding directly to their promoter. Stimulates also the expression of the mta gene itself, ydfK and ymfE.^{[1] [2]}

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

• Transcriptional activator 3D structures

References

1. ↑ Baranova NN, Danchin A, Neyfakh AA. Mta, a global MerR-type regulator of the Bacillus subtilis multidrug-efflux transporters. Mol Microbiol. 1999 Mar;31(5):1549-59. PMID:10200972
2. ↑ Miethke M, Schmidt S, Marahiel MA. The major facilitator superfamily-type transporter YmfE and the multidrug-efflux activator Mta mediate bacillibactin secretion in Bacillus subtilis. J Bacteriol. 2008 Aug;190(15):5143-52. Epub 2008 May 23. PMID:18502870 doi:http://dx.doi.org/JB.00464-08