1v5s

From Proteopedia

Solution structure of kinase associated domain 1 of mouse MAP/microtubule affinity-regulating kinase 3

Structural highlights

1v5s is a 1 chain structure with sequence from Mus musculus. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	Solution NMR
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

MARK3_MOUSE Involved in the specific phosphorylation of microtubule-associated proteins for tau, MAP2 and MAP4. Phosphorylates CDC25C. Regulates localization and activity of some histone deacetylases by mediating phosphorylation of HDAC7, promoting subsequent interaction between HDAC7 and 14-3-3 and export from the nucleus (By similarity).

Evolutionary Conservation

Checkto colour the structure by Evolutionary Conservation, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

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PDB ID 1v5s

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1v5s

From Proteopedia

Solution structure of kinase associated domain 1 of mouse MAP/microtubule affinity-regulating kinase 3

Structural highlights

Function

Evolutionary Conservation

See Also

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