1v63

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Solution structure of the 6th HMG box of mouse UBF1

Structural highlights

1v63 is a 1 chain structure with sequence from Mus musculus. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Solution NMR
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

UBF1_MOUSE Recognizes the ribosomal RNA gene promoter and activates transcription mediated by RNA polymerase I through cooperative interactions with the transcription factor SL1/TIF-IB complex. It binds specifically to the upstream control element.[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

  1. ↑ Pistoni M, Verrecchia A, Doni M, Guccione E, Amati B. Chromatin association and regulation of rDNA transcription by the Ras-family protein RasL11a. EMBO J. 2010 Apr 7;29(7):1215-24. doi: 10.1038/emboj.2010.16. Epub 2010 Feb 18. PMID:20168301 doi:http://dx.doi.org/10.1038/emboj.2010.16

Contents


PDB ID 1v63

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OCA

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