Structural highlights
Function
RCAN1_MOUSE Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development (PubMed:11231093).[1]
Evolutionary Conservation
Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.
References
- ↑ Casas C, Martínez S, Pritchard MA, Fuentes JJ, Nadal M, Guimerà J, Arbonés M, Flórez J, Soriano E, Estivill X, Alcántara S. Dscr1, a novel endogenous inhibitor of calcineurin signaling, is expressed in the primitive ventricle of the heart and during neurogenesis. Mech Dev. 2001 Mar;101(1-2):289-92. PMID:11231093 doi:10.1016/s0925-4773(00)00583-9