2qt5

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Crystal Structure of GRIP1 PDZ12 in Complex with the Fras1 Peptide

Structural highlights

2qt5 is a 4 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.3Å
Ligands:ACY, EDO
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

GRIP1_RAT May play a role as a localized scaffold for the assembly of a multiprotein signaling complex and as mediator of the trafficking of its binding partners at specific subcellular location in neurons.[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

  1. ↑ Dong H, O'Brien RJ, Fung ET, Lanahan AA, Worley PF, Huganir RL. GRIP: a synaptic PDZ domain-containing protein that interacts with AMPA receptors. Nature. 1997 Mar 20;386(6622):279-84. PMID:9069286 doi:http://dx.doi.org/10.1038/386279a0

Contents


PDB ID 2qt5

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OCA

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