2qzv

From Proteopedia

Draft Crystal Structure of the Vault Shell at 9 Angstroms Resolution

Structural highlights

2qzv is a 2 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 9Å
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

MVP_RAT Required for normal vault structure. Vaults are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo-cytoplasmic transport. Down-regulates INFG-mediated STAT1 signaling and subsequent activation of JAK. Down-regulates SRC activity and signaling through MAP kinases (By similarity).

Evolutionary Conservation

Checkto colour the structure by Evolutionary Conservation, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

1 Structural highlights
2 Function
3 Evolutionary Conservation

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PDB ID 2qzv

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2qzv

From Proteopedia

Draft Crystal Structure of the Vault Shell at 9 Angstroms Resolution

Structural highlights

Function

Evolutionary Conservation

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