3jqy

Structural highlights

Function

NEUO_ECOK1 Catalyzes the O-acetylation of capsular polymeric sialic acid. Shows high substrate specificity toward polymers of sialic acid that contains a large number of residues.^{[1] [2]}

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

1. ↑ Deszo EL, Steenbergen SM, Freedberg DI, Vimr ER. Escherichia coli K1 polysialic acid O-acetyltransferase gene, neuO, and the mechanism of capsule form variation involving a mobile contingency locus. Proc Natl Acad Sci U S A. 2005 Apr 12;102(15):5564-9. PMID:15809431 doi:10.1073/pnas.0407428102
2. ↑ Bergfeld AK, Claus H, Vogel U, Mühlenhoff M. Biochemical characterization of the polysialic acid-specific O-acetyltransferase NeuO of Escherichia coli K1. J Biol Chem. 2007 Jul 27;282(30):22217-27. PMID:17519228 doi:10.1074/jbc.M703044200