3qr7

Structural highlights

Function

SPIKE_BPP2 Forms the small spikes on the baseplate that plug the end of the tube before DNA ejection and form a channel perforating the host membrane during ejection. Involved in baseplate assembly.^{[1] [2]}

References

1. ↑ Yamashita E, Nakagawa A, Takahashi J, Tsunoda K, Yamada S, Takeda S. The host-binding domain of the P2 phage tail spike reveals a trimeric iron-binding structure. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Aug 1;67(Pt 8):837-41., Epub 2011 Jul 13. PMID:21821878 doi:10.1107/S1744309111005999
2. ↑ Browning C, Shneider MM, Bowman VD, Schwarzer D, Leiman PG. Phage pierces the host cell membrane with the iron-loaded spike. Structure. 2012 Feb 8;20(2):326-39. PMID:22325780 doi:10.1016/j.str.2011.12.009