3sx0

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Crystal structure of Dot1l in complex with a brominated SAH analog

Structural highlights

3sx0 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.28Å
Ligands:SO4, SX0, UNX
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

DOT1L_HUMAN Histone methyltransferase. Methylates 'Lys-79' of histone H3. Nucleosomes are preferred as substrate compared to free histones. Binds to DNA.

See Also

Contents


PDB ID 3sx0

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OCA

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