3w5s

Structural highlights

Function

GRAC_RHIS5 Involved in the gamma-resorcylate (2,6-dihydroxybenzoate) catabolism (PubMed:17158677). Catalyzes the reduction of maleylacetate to 3-oxoadipate (PubMed:17158677, PubMed:27040018).^{[1] [2]}

References

1. ↑ Yoshida M, Oikawa T, Obata H, Abe K, Mihara H, Esaki N. Biochemical and genetic analysis of the gamma-resorcylate (2,6-dihydroxybenzoate) catabolic pathway in Rhizobium sp. strain MTP-10005: identification and functional analysis of its gene cluster. J Bacteriol. 2007 Mar;189(5):1573-81. PMID:17158677 doi:10.1128/JB.01675-06
2. ↑ Fujii T, Sato A, Okamoto Y, Yamauchi T, Kato S, Yoshida M, Oikawa T, Hata Y. The crystal structure of maleylacetate reductase from Rhizobium sp. strain MTP-10005 provides insights into the reaction mechanism of enzymes in its original family. Proteins. 2016 Aug;84(8):1029-42. PMID:27040018 doi:10.1002/prot.25046