4b1r

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Tetracycline repressor class D mutant H100A in complex with iso-7- Chlortetracycline

Structural highlights

4b1r is a 1 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.95Å
Ligands:CL, ITC
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

TETR4_ECOLX TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

See Also

Contents


PDB ID 4b1r

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OCA

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