Structural highlights
Function
MCR_SULTO Catalyzes the reduction of malonyl-CoA to malonate semialdehyde, a key step in the 3-hydroxypropanoate and the 3-hydroxypropanoate/4-hydroxybutyrate cycles. Can also use succinyl-CoA and succinate semialdehyde as substrates but at a lower rate than malonyl-CoA.[1]
References
- ↑ Alber B, Olinger M, Rieder A, Kockelkorn D, Jobst B, Hugler M, Fuchs G. Malonyl-coenzyme A reductase in the modified 3-hydroxypropionate cycle for autotrophic carbon fixation in archaeal Metallosphaera and Sulfolobus spp. J Bacteriol. 2006 Dec;188(24):8551-9. Epub 2006 Oct 13. PMID:17041055 doi:http://dx.doi.org/10.1128/JB.00987-06
