Structural highlights
Function
GATA_YEAST Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Required for HMG2-induced ER-remodeling.[1] [2]
See Also
References
- ↑ Frechin M, Senger B, Braye M, Kern D, Martin RP, Becker HD. Yeast mitochondrial Gln-tRNA(Gln) is generated by a GatFAB-mediated transamidation pathway involving Arc1p-controlled subcellular sorting of cytosolic GluRS. Genes Dev. 2009 May 1;23(9):1119-30. doi: 10.1101/gad.518109. PMID:19417106 doi:http://dx.doi.org/10.1101/gad.518109
- ↑ Federovitch CM, Jones YZ, Tong AH, Boone C, Prinz WA, Hampton RY. Genetic and structural analysis of Hmg2p-induced endoplasmic reticulum remodeling in Saccharomyces cerevisiae. Mol Biol Cell. 2008 Oct;19(10):4506-20. Epub 2008 Jul 30. PMID:18667535 doi:http://dx.doi.org/E07-11-1188