4ojn

From Proteopedia

Crystal structure of human muscle L-lactate dehydrogenase

Structural highlights

4ojn is a 8 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 2.4Å
Ligands:	1PE, GOL
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Disease

LDHA_HUMAN Defects in LDHA are the cause of glycogen storage disease type 11 (GSD11) [MIM:612933. A metabolic disorder that results in exertional myoglobinuria, pain, cramps and easy fatigue.^[1]

Function

LDHA_HUMAN

References

↑ Maekawa M, Sudo K, Kanno T, Li SS. Molecular characterization of genetic mutation in human lactate dehydrogenase-A (M) deficiency. Biochem Biophys Res Commun. 1990 Apr 30;168(2):677-82. PMID:2334430

1 Structural highlights
2 Disease
3 Function
4 See Also
5 References

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PDB ID 4ojn

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Categories: Homo sapiens | Large Structures | Craig L | Kolappan S

4ojn

From Proteopedia

Crystal structure of human muscle L-lactate dehydrogenase

Structural highlights

Disease

Function

See Also

References

Contents

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