Structural highlights
5xn9 is a 2 chain structure with sequence from Ramazzottius varieornatus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
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| Method: | X-ray diffraction, Resolution 1.449Å |
| Ligands: | , , , , |
| Resources: | FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT |
Function
SAHS1_RAMVA Secreted heat soluble protein acting as a molecular shield in water-deficient condition (PubMed:22937162). Tardigrade-specific intrinsically disordered proteins (TDPs) are essential for desiccation tolerance by forming non-crystalline amorphous solids upon desiccation, and this vitrified state mirrors their protective capabilities (By similarity).[UniProtKB:P0CU39][1]
References
- ↑ Yamaguchi A, Tanaka S, Yamaguchi S, Kuwahara H, Takamura C, Imajoh-Ohmi S, Horikawa DD, Toyoda A, Katayama T, Arakawa K, Fujiyama A, Kubo T, Kunieda T. Two novel heat-soluble protein families abundantly expressed in an anhydrobiotic tardigrade. PLoS One. 2012;7(8):e44209. doi: 10.1371/journal.pone.0044209. Epub 2012 Aug 28. PMID:22937162 doi:http://dx.doi.org/10.1371/journal.pone.0044209
