6acv

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the solution NMR structure of MBD domain

Structural highlights

6acv is a 1 chain structure with sequence from Arabidopsis thaliana. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

MBD11_ARATH Transcriptional regulator that binds DNA independently of its methylation status. Required during plant organogenesis and development.[1] [2]

See Also

References

  1. Berg A, Meza TJ, Mahic M, Thorstensen T, Kristiansen K, Aalen RB. Ten members of the Arabidopsis gene family encoding methyl-CpG-binding domain proteins are transcriptionally active and at least one, AtMBD11, is crucial for normal development. Nucleic Acids Res. 2003 Sep 15;31(18):5291-304. doi: 10.1093/nar/gkg735. PMID:12954765 doi:http://dx.doi.org/10.1093/nar/gkg735
  2. Scebba F, Bernacchia G, De Bastiani M, Evangelista M, Cantoni RM, Cella R, Locci MT, Pitto L. Arabidopsis MBD proteins show different binding specificities and nuclear localization. Plant Mol Biol. 2003 Nov;53(5):715-31. doi: 10.1023/B:PLAN.0000019118.56822.a9. PMID:15010609 doi:http://dx.doi.org/10.1023/B:PLAN.0000019118.56822.a9

Contents


PDB ID 6acv

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