Structural highlights
Function
TYLH1_STRFR Involved in the biosynthesis of the complex macrolide antibiotic tylosin. Catalyzes the hydroxylation of 20-oxo-5-O-beta-mycaminosyltylactone at the C-23 position to yield 5-O-beta-mycaminosyltylonolide.[1]
References
- ↑ Baltz RH, Seno ET. Properties of Streptomyces fradiae mutants blocked in biosynthesis of the macrolide antibiotic tylosin. Antimicrob Agents Chemother. 1981 Aug;20(2):214-25. PMID:7283418