6ey7
From Proteopedia
Human cytomegalovirus terminase nuclease domain, Mn soaked, inhibitor bound
Structural highlights
Function[TRM3_HCMVA] Component of the molecular motor that translocates genomic DNA in empty capsid during DNA packaging. Heterodimerizes with small terminase protein to be docked on capsid portal protein. The latter forms a ring in which genomic DNA in translocated into the capsid. May have or induce an endonuclease activity to cleave the genome concatemer after encapsidation (By similarity).
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Categories: Hcmva | Albericio, F | Alvarez, M | Bongarzone, S | Coll, M | Kaczmarska, Z | Machon, C | Nadal, M | Cytomegalovirus | Drug design | Inhibitor | Raltegravir | Terminase | Ul89 | Viral protein