6ljo

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African swine fever virus dUTPase

Structural highlights

6ljo is a 1 chain structure with sequence from African swine fever virus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.28Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

DUTP_ASFB7 The viral dUTPase may play a role in lowering the dUTP concentration in natural infections to minimize misincorporation of deoxyuridine into the viral DNA and ensure the fidelity of genome replication.[1]

See Also

References

  1. Oliveros M, García-Escudero R, Alejo A, Viñuela E, Salas ML, Salas J. African swine fever virus dUTPase is a highly specific enzyme required for efficient replication in swine macrophages. J Virol. 1999 Nov;73(11):8934-43. PMID:10515998 doi:10.1128/JVI.73.11.8934-8943.1999

Contents


PDB ID 6ljo

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